RPA4

Gene Symbol RPA4
Entrez Gene 29935
Alt Symbol HSU24186
Species Human
Gene Type protein-coding
Description replication protein A4, 30kDa
Other Description RF-A protein 4|RP-A p30|replication factor A protein 4|replication protein A 30 kDa subunit|replication protein A complex 34 kd subunit homolog Rpa4|replication protein A4, 34kDa
Swissprots Q3SY03 Q13156
Accessions AAM09569 EAX02794 Q13156 BC069791 AAH69791 BC069808 AAH69808 BC069824 AAH69824 BC104013 AAI04014 BC104014 AAI04015 EU832763 ACE87774 GQ129306 ACT64440 HQ448414 ADQ32894 U24186 AAB08488 NM_013347 NP_037479
Function As part of the alternative replication protein A complex, aRPA, binds single-stranded DNA and probably plays a role in DNA repair. Compared to the RPA2-containing, canonical RPA complex, may not support chromosomal DNA replication and cell cycle progression through S-phase. The aRPA may not promote efficient priming by DNA polymerase alpha but could support DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC), the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange. {ECO:0000269|PubMed:19116208, ECO:0000269|PubMed:19942684, ECO:0000269|PubMed:19996105, ECO:0000269|PubMed:20545304}.
Subcellular Location Nucleus {ECO:0000269|PubMed:19942684}. Note=Localizes to DNA repair foci after DNA damage.
Tissue Specificity Preferentially expressed in placental and colon mucosa. Widely expressed at intermediate or lower levels. {ECO:0000269|PubMed:19996105}.
Top Pathways DNA replication, Mismatch repair, Homologous recombination, Nucleotide excision repair, Fanconi anemia pathway

Anti-RPA4 antibody - ab169032 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Immunofluorescent analysis of permeabilized HeLa cells labeling RPA4 with ab169032 at 10µg/ml.

Anti-RPA4 antibody - ab81772 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-RPA4 antibody (ab81772) at 1 µg/ml + fetal muscle lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-RPA4 antibody - ab135955 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-RPA4 antibody (ab135955) at 1/500 dilution + COLO205 cell extract at 30 µg

Anti-RPA4 antibody - C-terminal - ab200742 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-RPA4 antibody - C-terminal (ab200742)Lane 1 : HEK293T whole cell lysateLane 2 : Raw264.7 whole cell lysateLane 3 : PC12 whole cell lysate

Anti-RPA4 Antibody (aa212-261) - LS-C199987 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from COLO205 cells, using RPA30 antibody.

Anti-RPA4 Antibody (aa180-229) - LS-C111585 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
RPA4 antibody LS-C111585 Western blot of HeLa lysate.

Anti-RPA4 Antibody (C-Terminus) - LS-C81967 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Fetal muscle lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-RPA4 Antibody (aa233-261, APC) - LS-C240183 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RPA4 Antibody (aa233-261, Biotin) - LS-C240184 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RPA4 Antibody (aa233-261, PE) - LS-C240187 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RPA4 Antibody (aa233-261, FITC) - LS-C240185 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RPA4 Antibody (aa233-261, Azide-free, HRP) - LS-C248038 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RPA4 Antibody (aa233-261) - LS-C324767 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RPA4 Antibody (aa234-261) - LS-C158883 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
RPA4 Antibody western blot of K562 cell line lysates (35 ug/lane). The RPA4 antibody detected the RPA4 protein (arrow).

Anti-RPA4 Antibody (aa233-261, AP) - LS-C240181 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

RPA4 Antibody - H00029935-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

RPA4 Antibody - NBP1-58157 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: RPA4 Antibody [NBP1-58157] - Human Muscle lysate, concentration 0.2-1 ug/ml.

RPA4 Antibody - NBP1-58156 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: RPA4 Antibody [NBP1-58156] - Hela cell lysate, concentration 0.2-1 ug/ml.

RPA4 Antibody - NBP1-31860 from Novus Biologicals

Host Rabbit
Clonality Polyclonal

RPA4 Antibody - H00029935-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: RPA4 Antibody [H00029935-D01P] - Analysis of RPA4 expression in human kidney.

RPA4 Antibody - H00029935-D01 from Novus Biologicals

Prices $399.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-RPA4 antibody produced in mouse - SAB1400521 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Polyclonal Anti-RPA4, antibody produced in mouse, purified immunoglobulin: <B>Cat. No. SAB1400521</B>: Antibody concentration: 3.0 μg/mL using human human placenta tissue.

Anti-RPA4 (ab2) antibody produced in rabbit - SAB2102049 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-RPA4 (ab2): <B>Cat. No.SAB2102049</B>: RPA4 in HeLa cell lysate with RPA4 antibody at 1.0 μg/mL.

Anti-RPA4 (ab1) antibody produced in rabbit - SAB2102048 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-RPA4 (ab1): <B>Cat. No.SAB2102048</B>: RPA4 in Fetal Muscle tissue lysate with RPA4 antibody at 1.0 μg/mL.

Anti-RPA4 antibody produced in rabbit - SAB1410607 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-RPA4: <B>Cat. No. SAB1410607</B>: Antibody concentration: 1-5 μg/mL. Specific band of ~28.9 kDa using human kidney lysate.
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