RPA4

Gene Symbol	RPA4
Entrez Gene	29935
Alt Symbol	HSU24186
Species	Human
Gene Type	protein-coding
Description	replication protein A4, 30kDa
Other Description	RF-A protein 4|RP-A p30|replication factor A protein 4|replication protein A 30 kDa subunit|replication protein A complex 34 kd subunit homolog Rpa4|replication protein A4, 34kDa
Swissprots	Q3SY03 Q13156
Accessions	AAM09569 EAX02794 Q13156 BC069791 AAH69791 BC069808 AAH69808 BC069824 AAH69824 BC104013 AAI04014 BC104014 AAI04015 EU832763 ACE87774 GQ129306 ACT64440 HQ448414 ADQ32894 U24186 AAB08488 NM_013347 NP_037479
Function	As part of the alternative replication protein A complex, aRPA, binds single-stranded DNA and probably plays a role in DNA repair. Compared to the RPA2-containing, canonical RPA complex, may not support chromosomal DNA replication and cell cycle progression through S-phase. The aRPA may not promote efficient priming by DNA polymerase alpha but could support DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC), the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange. {ECO:0000269|PubMed:19116208, ECO:0000269|PubMed:19942684, ECO:0000269|PubMed:19996105, ECO:0000269|PubMed:20545304}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:19942684}. Note=Localizes to DNA repair foci after DNA damage.
Tissue Specificity	Preferentially expressed in placental and colon mucosa. Widely expressed at intermediate or lower levels. {ECO:0000269|PubMed:19996105}.
Top Pathways	DNA replication, Mismatch repair, Homologous recombination, Nucleotide excision repair, Fanconi anemia pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

RPA4 293T Cell Transient Overexpression Lysate(Denatured) - H00029935-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

RPA4 overexpression lysate - LY415651 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

RPA4 293 Cell Lysate - 407360 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

RPA4 Overexpression Lysate (Denatured) - H00029935-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

RPA4 Overexpression Lysate (Native) - NBL1-15491 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

RPA4 Over-expression Lysate Product - GWB-60C3E0 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Panoply™ Human RPA4 Knockdown Stable Cell Line - CSC-DC013482 from Creative biogene Category Cell Line Species Human

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