RPA4

Gene Symbol RPA4
Entrez Gene 29935
Alt Symbol HSU24186
Species Human
Gene Type protein-coding
Description replication protein A4, 30kDa
Other Description RF-A protein 4|RP-A p30|replication factor A protein 4|replication protein A 30 kDa subunit|replication protein A complex 34 kd subunit homolog Rpa4|replication protein A4, 34kDa
Swissprots Q3SY03 Q13156
Accessions AAM09569 EAX02794 Q13156 BC069791 AAH69791 BC069808 AAH69808 BC069824 AAH69824 BC104013 AAI04014 BC104014 AAI04015 EU832763 ACE87774 GQ129306 ACT64440 HQ448414 ADQ32894 U24186 AAB08488 NM_013347 NP_037479
Function As part of the alternative replication protein A complex, aRPA, binds single-stranded DNA and probably plays a role in DNA repair. Compared to the RPA2-containing, canonical RPA complex, may not support chromosomal DNA replication and cell cycle progression through S-phase. The aRPA may not promote efficient priming by DNA polymerase alpha but could support DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC), the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange. {ECO:0000269|PubMed:19116208, ECO:0000269|PubMed:19942684, ECO:0000269|PubMed:19996105, ECO:0000269|PubMed:20545304}.
Subcellular Location Nucleus {ECO:0000269|PubMed:19942684}. Note=Localizes to DNA repair foci after DNA damage.
Tissue Specificity Preferentially expressed in placental and colon mucosa. Widely expressed at intermediate or lower levels. {ECO:0000269|PubMed:19996105}.
Top Pathways DNA replication, Mismatch repair, Homologous recombination, Nucleotide excision repair, Fanconi anemia pathway

Human RPA4 full length protein - ab162273 from Abcam

Category Protein
Source Wheat germ
Species Human
ab162273 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Human RPA4 protein fragment - ab162274 from Abcam

Category Protein
Source Wheat germ
Species Human
ab162274 on a 12.5% SDS-PAGE stained with Coomassie Blue.

RPA4 Antibody Blocking Peptide - LS-E6127 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

RPA4 Antibody Blocking Peptide - LS-E19817 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

RPA4 Antibody Blocking Peptide - LS-E19818 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

RPA4 Recombinant Protein - H00029935-P01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

RPA4 Partial Recombinant Protein - H00029935-Q01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

RPA4-Antibody-C-term-Blocking-Peptide - BP18746b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

Human RPA4 protein - orb245642 from Biorbyt

Category Protein
Prices $340.00, $629.00, $1,003.00, $1,556.00
Sizes 50 μg, 200 μg, 500 μg, 1 mg
Species Human

RPA4 Blocking Peptide - 33R-3818 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

RPA4 Blocking Peptide - 33R-9743 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

RPA4 Blocking Peptide - abx161213 from Abbexa

Category Peptide
Species Human, Mouse, Rat

RPA4 - H00029935-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

RPA4 - H00029935-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

RPA4 - H00029935-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

RPA4 - H00029935-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

RPA4 fusion protein - ag12791 from Proteintech Group

Category Protein
Source E. coli-derived, PET28a
Species Human

RPA4 fusion protein - Ag12800 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PGEX-4T
Species Human

Recombinant Human RPA4, His-tagged - RPA4-2367H from Creative Biomart

Category Protein
Source E.coli
Species Human

RPA4 Blocking Peptide - CBP3712 from Cohesion Biosciences

Category Peptide
Prices $100.00, $300.00
Sizes 1 mg, 5 mg
Species Human, Mouse, Rat

Recombinant human Replication protein A 30 kDa subunit - CSB-EP162494h CSB-BP162494h CSB-MP162494h from Cusabio

Category Protein
Source E.coli or Baculovirus or Mammalian cell
Species Human

Recombinant Human Replication protein A 30 kDa subunit(RPA4),partial - CSB-RP162494h from Cusabio

Category Protein
Source E.coli
Species Human

Recombinant Human Replication protein A 30 kDa subunit(RPA4) - CSB-YP622640HU CSB-EP622640HU CSB-BP622640HU CSB-MP622640HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

RPA4 Protein - abx163138 from Abbexa

Category Protein
Species Human

RPA4 - TP310239 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
RPA4
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