RPA4

Gene Symbol RPA4
Entrez Gene 29935
Alt Symbol HSU24186
Species Human
Gene Type protein-coding
Description replication protein A4, 30kDa
Other Description RF-A protein 4|RP-A p30|replication factor A protein 4|replication protein A 30 kDa subunit|replication protein A complex 34 kd subunit homolog Rpa4|replication protein A4, 34kDa
Swissprots Q3SY03 Q13156
Accessions AAM09569 EAX02794 Q13156 BC069791 AAH69791 BC069808 AAH69808 BC069824 AAH69824 BC104013 AAI04014 BC104014 AAI04015 EU832763 ACE87774 GQ129306 ACT64440 HQ448414 ADQ32894 U24186 AAB08488 NM_013347 NP_037479
Function As part of the alternative replication protein A complex, aRPA, binds single-stranded DNA and probably plays a role in DNA repair. Compared to the RPA2-containing, canonical RPA complex, may not support chromosomal DNA replication and cell cycle progression through S-phase. The aRPA may not promote efficient priming by DNA polymerase alpha but could support DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC), the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange. {ECO:0000269|PubMed:19116208, ECO:0000269|PubMed:19942684, ECO:0000269|PubMed:19996105, ECO:0000269|PubMed:20545304}.
Subcellular Location Nucleus {ECO:0000269|PubMed:19942684}. Note=Localizes to DNA repair foci after DNA damage.
Tissue Specificity Preferentially expressed in placental and colon mucosa. Widely expressed at intermediate or lower levels. {ECO:0000269|PubMed:19996105}.
Top Pathways DNA replication, Mismatch repair, Homologous recombination, Nucleotide excision repair, Fanconi anemia pathway

RPA 34 kDa subunit CRISPR/Cas9 KO Plasmid (h) - sc-412050 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

RPA 34 kDa subunit HDR Plasmid (h) - sc-412050-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RPA 34 kDa subunit Double Nickase Plasmid (h) - sc-412050-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RPA 34 kDa subunit Double Nickase Plasmid (h2) - sc-412050-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RPA 34 kDa subunit CRISPR Activation Plasmid (h) - sc-412050-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

RPA 34 kDa subunit CRISPR Activation Plasmid (h2) - sc-412050-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

RPA 34 kDa subunit Lentiviral Activation Particles (h) - sc-412050-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RPA 34 kDa subunit Lentiviral Activation Particles (h2) - sc-412050-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RPA 34 kDa subunit siRNA (h) - sc-91267 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

RPA 34 kDa subunit shRNA Plasmid (h) - sc-91267-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

RPA 34 kDa subunit shRNA (h) Lentiviral Particles - sc-91267-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

RPA4 RNAi - H00029935-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU103181 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN18518 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18518 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR03914 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr03914

RPA4 siRNA (Human) - CRH9280 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

RPA4 - MBS8225466 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human RPA4 (NM_013347.4) - SHH397884 from Creative biogene

Category siRNA
Species Reactivities Human

Human RPA4 siRNA - orb269782 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

RPA4 shRNA Plasmid (Human) - CHH9280 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

RPA4 miRNA 3'UTR clone - MiUTR4H-TG07629 from Creative biogene

Species Reactivities Human
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