TNFRSF12A

Gene Symbol	TNFRSF12A
Entrez Gene	51330
Alt Symbol	CD266, FN14, TWEAKR
Species	Human
Gene Type	protein-coding
Description	tumor necrosis factor receptor superfamily, member 12A
Other Description	FGF-inducible 14|fibroblast growth factor-inducible immediate-early response protein 14|tumor necrosis factor receptor superfamily member 12A|tweak-receptor|type I transmembrane protein Fn14
Swissprots	Q9NP84 Q9HCS0 D3DUA6
Accessions	CAI54172 CAL48784 CCA61735 CCA61738 EAW85428 EAW85429 EAW85430 Q9NP84 AB035480 BAA94792 AB035481 BAB17850 AF191148 AAF69108 BC002718 AAH02718 BC020538 BC064377 BM842283 DQ892968 ABM83894 DQ896216 ABM87215 NM_016639 NP_057723
Function	Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins. {ECO:0000269|PubMed:11728344}.
Subcellular Location	Membrane; Single-pass type I membrane protein.
Tissue Specificity	Highly expressed in heart, placenta and kidney. Intermediate expression in lung, skeletal muscle and pancreas.
Top Pathways	Cytokine-cytokine receptor interaction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human TWEAKR protein fragment - ab117223 from Abcam Category Protein Prices $465.00 Sizes 25 µg Source E. coli Species Human

Active human TWEAKR protein fragment - ab151353 from Abcam Category Protein Source HEK 293 cells Species Human

Active human TWEAKR protein fragment - ab182702 from Abcam Category Protein Prices $536.00 Sizes 100 µg Source HEK 293 cells Species Human

Active human TWEAKR protein fragment - ab201431 from Abcam Category Protein Prices $101.00 Sizes 5 µg Source E. coli Species Human

Active human TWEAKR protein fragment - ab50176 from Abcam Category Protein Prices $110.00, $257.00 Sizes 5 µg, 25 µg Source E. coli Species Human

Active human TWEAKR protein fragment - ab125756 from Abcam Category Protein Prices $192.00 Sizes 25 µg Source E. coli Species Human

Active mouse TWEAKR protein fragment - ab157284 from Abcam Category Protein Prices $410.00 Sizes 50 µg Source HEK 293 cells Species Mouse

Human TWEAKR protein fragment - ab186090 from Abcam Category Protein Source Mammalian Species Human

Human TWEAKR protein fragment - ab109167 from Abcam Category Protein Source HEK 293 cells Species Human

Mouse TWEAKR protein fragment - ab185863 from Abcam Category Protein Source Mammalian Species Mouse

TNFRSF12A / FN14 Antibody Blocking Peptide - LS-E18482 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human TWEAK R/TNFRSF12 Protein - NBP2-35085 from Novus Biologicals Category Protein Prices $69.00, $149.00, $2,669.00 Sizes 5 µg, 25 µg, 1 mg Source E. coli Species Human

Recombinant Human TWEAK R/TNFRSF12 Protein - H00051330-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Source Wheat Germ Species Human

TWEAKR Recombinant Protein (Active) - GTX48010-PRO from GeneTex Category Protein Prices $299.00 Sizes 25 μg Source E. coli Species Human

Recombinant Human TWEAK R/TNFRSF12 Fc Chimera, CF - 1199-TW-050 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived

TNFRSF12A Protein (OOPA00054) - OOPA00054 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source Escherichia Coli.

Human CD266 Protein (OPSA11772) - OPSA11772 from Aviva Systems Biology Category Protein Prices $440.00 Sizes 25 µg Species Human

Human TNFRSF12A protein - orb169449 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 25 μg Source E. coli

Human TNFRSF12A protein - orb139770 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source Human Cells Species Human

Human TWEAK Receptor protein - orb107810 from Biorbyt Category Protein Prices $221.00, $357.00, $553.00, $910.00 Sizes 5 μg, 25 μg, 100 μg, 250 μg Source E.coli

Human FN14 protein - orb180449 from Biorbyt Category Protein Prices $306.00, $400.00, $1,904.00, $2,695.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Species Human

TWEAK Receptor protein - 30R-AT080 from Fitzgerald Category Protein Prices $225.00 Sizes 25 µg Source E.coli

CD266 / TweakR - PA263 from Acris Antibodies Category Protein Prices $135.00 Sizes 5 µg Source E. coli Species Human

CD266 / TweakR - PA263X from Acris Antibodies Category Protein Prices $235.00 Sizes 25 µg Source E. coli Species Human

CD266 / TweakR - H00051330-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Search more