TNFRSF12A

Gene Symbol TNFRSF12A
Entrez Gene 51330
Alt Symbol CD266, FN14, TWEAKR
Species Human
Gene Type protein-coding
Description tumor necrosis factor receptor superfamily, member 12A
Other Description FGF-inducible 14|fibroblast growth factor-inducible immediate-early response protein 14|tumor necrosis factor receptor superfamily member 12A|tweak-receptor|type I transmembrane protein Fn14
Swissprots Q9NP84 Q9HCS0 D3DUA6
Accessions CAI54172 CAL48784 CCA61735 CCA61738 EAW85428 EAW85429 EAW85430 Q9NP84 AB035480 BAA94792 AB035481 BAB17850 AF191148 AAF69108 BC002718 AAH02718 BC020538 BC064377 BM842283 DQ892968 ABM83894 DQ896216 ABM87215 NM_016639 NP_057723
Function Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins. {ECO:0000269|PubMed:11728344}.
Subcellular Location Membrane; Single-pass type I membrane protein.
Tissue Specificity Highly expressed in heart, placenta and kidney. Intermediate expression in lung, skeletal muscle and pancreas.
Top Pathways Cytokine-cytokine receptor interaction

TWEAK Receptor/Fn14 Antibody - 4403 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from HT-1080, PC3 and HT29 cell lines, using TWEAK Receptor/Fn14 Antibody.

Fn14 (N-21) - sc-27141 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Fn14 (D-13) - sc-27142 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Fn14 (D-13): sc-27142. Immunoperoxidase staining of formalin fixed, paraffin-embedded human fallopian tube tissue showing cytoplasmic and membrane staining of glandular cells.

Fn14 (C-13) - sc-27143 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-TWEAKR antibody - ab62496 from Abcam

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-TWEAKR antibody (ab62496) at 1 µg/mlLane 1 : mock transfected 293 cells Lane 2 : Fn14-GPI transfected 293 cellsLysates/proteins at 15 µg per lane.

Anti-TWEAKR antibody - ab85089 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of TWEAKR expression in paraffin embedded formalin fixed liver using 1/100 ab85089. Note membrane staining.

Anti-TWEAKR antibody - ab125380 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-TWEAKR antibody (ab125380) at 1 µg/ml + Mouse kidney lysate at 10 µgSecondaryGoat anti-Rabbit IgG HRP

Anti-TWEAKR antibody [ ITEM-4] (Biotin) - ab93554 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone ITEM-4
ab93554 at 0.25µg dilution staining TWEAKR in non-transfected L5178Y cells (left image) and TWEAKR transfected L5178Y cells (right image) by Flow Cytometry

Anti-TWEAKR antibody [EPR3179] - ab109365 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR3179
All lanes : Anti-TWEAKR antibody [EPR3179] (ab109365) at 1/1000 dilutionLane 1 : HT-29 cell lysateLane 2 : HUVEC cell lysateLane 3 : HT-1080 cell lysateLysates/proteins at 10 µg per lane.

Anti-TWEAKR antibody [ITEM-1] - ab21359 from Abcam

Prices $372.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone ITEM-1

Anti-TWEAKR antibody [ITEM-4] - ab21127 from Abcam

Prices $373.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone ITEM-4

Anti-TWEAKR antibody [ITEM-4] (FITC) - ab117262 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone ITEM-4
ab117262 at 10µl/106 cells staining TWEAKR in Human TWEAKR transfected cells by Flow Cytometry.

Anti-TWEAKR antibody [ITEM-4] (Phycoerythrin) - ab93555 from Abcam

Prices $376.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone ITEM-4
ab93555 at 0.5µg dilution staining TWEAKR in non-transfected L5178Y cells by Flow Cytometry (shown in blue).

Anti-TWEAKR antibody [ITEM4] (Phycoerythrin) - ab191107 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone ITEM4

Anti-TNFRSF12A / TWEAK Receptor Antibody - LS-C48523 from LifeSpan Bioscience

Prices $445.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-TNFRSF12A / TWEAK Receptor Antibody - LS-C124744 from LifeSpan Bioscience

Prices $335.00
Sizes 25 µg
Host Mouse
Clonality Monoclonal

Anti-TNFRSF12A / TWEAK Receptor Antibody - LS-C150061 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-TNFRSF12A / TWEAK Receptor Antibody - LS-C150267 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-TNFRSF12A / TWEAK Receptor Antibody (clone ITEM-1) - LS-C40819 from LifeSpan Bioscience

Prices $285.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone ITEM-1
Human Fn14 transfected cells stained with purified ITEM-1, followed by anti-mouse IgG FITC

Anti-TNFRSF12A / TWEAK Receptor Antibody (C-Terminus, clone SP134) - LS-C210377 from LifeSpan Bioscience

Prices $530.00
Sizes 500 µl
Host Rabbit
Clonality Monoclonal
Clone SP134
Immunohistochemistry of Human Lung stained with anti-FN14 antibody

Anti-TNFRSF12A / TWEAK Receptor Antibody IHC-plus™ - LS-B605 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-TWEAKR antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B605 concentration 5 ug/ml.

Anti-TNFRSF12A / TWEAK Receptor Antibody (clone ITEM-4) - LS-C188542 from LifeSpan Bioscience

Prices $250.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone ITEM-4

Anti-TNFRSF12A / TWEAK Receptor Antibody (aa104-118) - LS-C837 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of TweakR in A) human liver lysate, B) mouse liver tissue lysate, and C) rat liver lysate using antibody at 1:500.

Anti-TNFRSF12A / TWEAK Receptor Antibody - LS-C343693 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-TNFRSF12A / TWEAK Receptor Antibody (N-Terminus) - LS-C146338 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
TNFRSF12A / TWEAKR antibody LS-C146338 Western blot of Mouse Kidney lysate. Antibody concentration 1 ug/ml.
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