YY1

Gene Symbol YY1
Entrez Gene 7528
Alt Symbol DELTA, INO80S, NF-E1, UCRBP, YIN-YANG-1
Species Human
Gene Type protein-coding
Description YY1 transcription factor
Other Description INO80 complex subunit S|YY-1|Yin and Yang 1 protein|delta transcription factor|transcriptional repressor protein YY1
Swissprots P25490 Q14935
Accessions EAW81689 EAW81690 P25490 AF147416 AK025731 AK026497 BC014138 BC020324 BC037308 AAH37308 BC065366 AAH65366 BX647456 DA234524 DQ891638 ABM82564 EU176600 ABW03401 M76541 AAA59926 M77698 AAA59467 Z14077 CAA78455 NM_003403 NP_003394
Function Multifunctional transcription factor that exhibits positive and negative control on a large number of cellular and viral genes by binding to sites overlapping the transcription start site. Binds to the consensus sequence 5'-CCGCCATNTT-3'; some genes have been shown to contain a longer binding motif allowing enhanced binding; the initial CG dinucleotide can be methylated greatly reducing the binding affinity. The effect on transcription regulation is depending upon the context in which it binds and diverse mechanisms of action include direct activation or repression, indirect activation or repression via cofactor recruitment, or activation or repression by disruption of binding sites or conformational DNA changes. Its activity is regulated by transcription factors and cytoplasmic proteins that have been shown to abrogate or completely inhibit YY1-mediated activation or repression. For example, it acts as a repressor in absence of adenovirus E1A protein but as an activator in its presenc
Subcellular Location Nucleus matrix {ECO:0000269|PubMed:18026119, ECO:0000269|PubMed:23385818, ECO:0000269|PubMed:9493912}. Note=Associated with the nuclear matrix.

YY1 (13G10) Rabbit mAb - 2185 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone 13G10
Western blot analysis of total cell lysates from C6 and PC12 cells, using YY1 (13G10) Rabbit mAb.

YY1 (C-20) - sc-281 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
YY1 (C-20): sc-281. Western blot analysis of YY1 expression in HeLa (A), A-431 (B), Y79 (C) and NIH/3T3 (D) whole cell lysates.

YY1 (H-10) - sc-7341 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
YY1 (H-10): sc-7341. Immunoperoxidase staining of formalin-fixed, paraffin-embedded normal human colon showing nuclear localization.

YY1 (H-414) - sc-1703 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
YY1 (H-414): sc-1703. Western blot analysis of YY1 expression in Y79 nuclear extract.

Anti-YY1 antibody - ab58068 from Abcam

Prices $384.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
YY1 antibody (ab58068) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human small Intestine.

Anti-YY1 antibody - ab58066 from Abcam

Prices $378.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
YY1 antibody (ab58066) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human lung.

Anti-YY1 antibody - ab38423 from Abcam

Prices $378.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-YY1 antibody (ab38423) at 1/100 dilution + Hela cell lysateSecondaryHRP-anti-rabbitdeveloped using the ECL technique

Anti-YY1 antibody - ab49145 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-YY1 antibody (ab49145) at 1 µg/ml + Fetal thymus lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-YY1 antibody [2C4] - ab189144 from Abcam

Prices $384.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 2C4
Anti-YY1 antibody [2C4] (ab189144) + HeLa nuclear extract

Anti-YY1 antibody [4D2] - ab117717 from Abcam

Prices $384.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 4D2
Immunohistochemistry Image of Formalin-Fixed Paraffin-Embedded Human, Testis stained with anti-YY1 antibody (ab117717) at 5 µg/ml.

Anti-YY1 antibody [EPR4651] - ab109228 from Abcam

Prices $99.00, $379.00
Sizes 10 µl, 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4651
All lanes : Anti-YY1 antibody [EPR4651] (ab109228) at 1/1000 dilutionLane 1 : HeLa cell lysatesLane 2 : Y79 cell lysatesLane 3 : HuT-78 cell lysatesLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-YY1 antibody [EPR4652] - Nuclear Loading Control - ab109237 from Abcam

Prices $395.00, $791.00
Sizes 100 µl, 250 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4652
All lanes : Anti-YY1 antibody [EPR4652] - Nuclear Loading Control (ab109237) at 1/10000 dilution (purified)Lane 1 : HeLa cell lysateLane 2 : Daudi cell lysateLysates/proteins at 20 µg per lane.SecondaryPeroxidase-conjugated goat anti-rabbit IgG (H+L) at 1/1000 dilution

Anti-YY1 antibody [EPR4652] - Nuclear Marker (Alexa Fluor® 488) - ab199814 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4652
ab199814 staining YY1 in HeLa cells. The cells were fixed with 100% methanol (5 min), permeabilized with 0.1% Triton X-100 for 5 minutes and then blocked with 1% BSA/10% normal goat serum/0.3M glycine in 0.1% PBS-Tween for 1h. The cells were then incubated overnight at +4°C with ab at a 1/100 dilution (shown in green) and ab195889, Mouse monoclonal to alpha Tubulin (Alexa Fluor® 594), at a 1/250 dilution (shown in red). Nuclear DNA was labelled with DAPI (shown in blue).Image was taken with a confocal microscope (Leica-Microsystems, TCS SP8).This product also gave a positive signal under the same testing conditions in HeLa cells fixed with 4% formaldehyde (10 min).

Anti-YY1 antibody [EPR4652] - Nuclear Marker (Alexa Fluor® 647) - ab199815 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4652
ab199815 staining YY1 in HeLa cells. The cells were fixed with 4% formaldehyde (10 min), permeabilized with 0.1% Triton X-100 for 5 minutes and then blocked with 1% BSA/10% normal goat serum/0.3M glycine in 0.1% PBS-Tween for 1h. The cells were then incubated overnight at +4°C with ab at a 1/100 dilution (shown in red) and ab195887, Mouse monoclonal to alpha Tubulin (Alexa Fluor® 488), at a 1/250 dilution (shown in green). Nuclear DNA was labelled with DAPI (shown in blue).Image was taken with a confocal microscope (Leica-Microsystems, TCS SP8).This product also gave a positive signal under the same testing conditions in HeLa cells fixed with 100% methanol (5 min).

Anti-YY1 antibody - ChIP Grade - ab12132 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-YY1 antibody - ChIP Grade - ab38422 from Abcam

Prices $379.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-YY1 antibody - ChIP Grade (ab38422) at 1/100 dilutionLane 1 : HL60 cell lysateLane 2 : Mouse kidney tissue lysate

Anti-YY1 antibody - Nuclear Loading Control - ab43058 from Abcam

Prices $385.00, $770.00
Sizes 100 µg, 250 µg
Host Rabbit
Clonality Polyclonal
Anti-YY1 antibody - Nuclear Loading Control (ab43058) at 2 µg/ml + Jurkat (Human T cell lymphoblast-like cell line) Nuclear Lysate (ab14844) at 20 µgSecondaryIRDye 680 Conjugated Goat Anti-Rabbit IgG (H+L) at 1/10000 dilutionPerformed under reducing conditions.

Anti-YY1 Antibody (clone 4D2) IHC-plus™ - LS-B5551 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 4D2
Anti-YY1 antibody IHC of human, testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5551 concentration 5 ug/ml.

Anti-YY1 Antibody (clone 3248C3a) - LS-C342678 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3248C3a
Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.1% Triton X-100 in PBS. The cells were immunostained with anti-YY1 mAb.

Anti-YY1 Antibody - LS-C10834 from LifeSpan Bioscience

Prices $475.00
Sizes 150 µg
Host Mouse
Clonality Monoclonal

Anti-YY1 Antibody - LS-C76484 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal

Anti-YY1 Antibody - LS-C126394 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-YY1 Antibody (aa197-246) - LS-C30080 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Fetal Thymus Lysate

Anti-YY1 Antibody (N-Terminus) - LS-C30213 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
A: Marker, B: Jurkat Cell Lysate

Anti-YY1 Antibody (aa274-323) - LS-C29977 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
YY1 antibody LS-C29977 was used in IHC to stain formalin-fixed, paraffin-embedded human muscle.
Search more