YY1

Gene Symbol	YY1
Entrez Gene	7528
Alt Symbol	DELTA, INO80S, NF-E1, UCRBP, YIN-YANG-1
Species	Human
Gene Type	protein-coding
Description	YY1 transcription factor
Other Description	INO80 complex subunit S|YY-1|Yin and Yang 1 protein|delta transcription factor|transcriptional repressor protein YY1
Swissprots	P25490 Q14935
Accessions	EAW81689 EAW81690 P25490 AF147416 AK025731 AK026497 BC014138 BC020324 BC037308 AAH37308 BC065366 AAH65366 BX647456 DA234524 DQ891638 ABM82564 EU176600 ABW03401 M76541 AAA59926 M77698 AAA59467 Z14077 CAA78455 NM_003403 NP_003394
Function	Multifunctional transcription factor that exhibits positive and negative control on a large number of cellular and viral genes by binding to sites overlapping the transcription start site. Binds to the consensus sequence 5'-CCGCCATNTT-3'; some genes have been shown to contain a longer binding motif allowing enhanced binding; the initial CG dinucleotide can be methylated greatly reducing the binding affinity. The effect on transcription regulation is depending upon the context in which it binds and diverse mechanisms of action include direct activation or repression, indirect activation or repression via cofactor recruitment, or activation or repression by disruption of binding sites or conformational DNA changes. Its activity is regulated by transcription factors and cytoplasmic proteins that have been shown to abrogate or completely inhibit YY1-mediated activation or repression. For example, it acts as a repressor in absence of adenovirus E1A protein but as an activator in its presenc
Subcellular Location	Nucleus matrix {ECO:0000269|PubMed:18026119, ECO:0000269|PubMed:23385818, ECO:0000269|PubMed:9493912}. Note=Associated with the nuclear matrix.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

YY1 293T Cell Transient Overexpression Lysate(Denatured) - H00007528-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

YY1 overexpression lysate - LY401166 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

YY1 293 Cell Lysate - 401082 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

YY1 Overexpression Lysate (Denatured) - H00007528-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

YY1 Overexpression Lysate (Native) - NBL1-17953 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

YY1 (h2): 293T Lysate - sc-172170 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

YY1 Over-expression Lysate Product - GWB-E0C058 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

YY1 Overexpression Lysate (Denatured) - H00007528-T03 from Novus Biologicals Category Cell Lysate Prices $299.00 Sizes 100 µl

YY1 Overexpression Lysate (Denatured) - H00007528-T02 from Novus Biologicals Category Cell Lysate Prices $299.00 Sizes 100 µl

Panoply™ Human YY1 Knockdown Stable Cell Line - CSC-DC017648 from Creative biogene Category Cell Line Species Human

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