YY1

Gene Symbol	YY1
Entrez Gene	7528
Alt Symbol	DELTA, INO80S, NF-E1, UCRBP, YIN-YANG-1
Species	Human
Gene Type	protein-coding
Description	YY1 transcription factor
Other Description	INO80 complex subunit S|YY-1|Yin and Yang 1 protein|delta transcription factor|transcriptional repressor protein YY1
Swissprots	P25490 Q14935
Accessions	EAW81689 EAW81690 P25490 AF147416 AK025731 AK026497 BC014138 BC020324 BC037308 AAH37308 BC065366 AAH65366 BX647456 DA234524 DQ891638 ABM82564 EU176600 ABW03401 M76541 AAA59926 M77698 AAA59467 Z14077 CAA78455 NM_003403 NP_003394
Function	Multifunctional transcription factor that exhibits positive and negative control on a large number of cellular and viral genes by binding to sites overlapping the transcription start site. Binds to the consensus sequence 5'-CCGCCATNTT-3'; some genes have been shown to contain a longer binding motif allowing enhanced binding; the initial CG dinucleotide can be methylated greatly reducing the binding affinity. The effect on transcription regulation is depending upon the context in which it binds and diverse mechanisms of action include direct activation or repression, indirect activation or repression via cofactor recruitment, or activation or repression by disruption of binding sites or conformational DNA changes. Its activity is regulated by transcription factors and cytoplasmic proteins that have been shown to abrogate or completely inhibit YY1-mediated activation or repression. For example, it acts as a repressor in absence of adenovirus E1A protein but as an activator in its presenc
Subcellular Location	Nucleus matrix {ECO:0000269|PubMed:18026119, ECO:0000269|PubMed:23385818, ECO:0000269|PubMed:9493912}. Note=Associated with the nuclear matrix.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human YY1 full length protein - ab152809 from Abcam Category Protein Source Wheat germ Species Human

Human YY1 full length protein - ab187479 from Abcam Category Protein Source E. coli Species Human

Human YY1 peptide - ab45370 from Abcam Category Peptide

Human YY1 protein fragment - ab112373 from Abcam Category Protein Source Wheat germ Species Human

YY1 Antibody Blocking Peptide - LS-E10903 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

YY1 Antibody Blocking Peptide - LS-E13758 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

YY1 Antibody Blocking Peptide - LS-E6980 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

YY1 Antibody Blocking Peptide - LS-E6981 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

YY1 Antibody Blocking Peptide - LS-E6551 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

YY1 Recombinant Protein - H00007528-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Species Human

YY1 Partial Recombinant Protein - H00007528-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

YY1 Peptide - P1131 from Novus Biologicals Category Peptide Species Human

YY1 Peptide - P1130 from Novus Biologicals Category Peptide Species Human

YY1-Antibody-Center-Blocking-Peptide - BP19325c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

YY1-Antibody-Center-Blocking-Peptide - BP2517c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

YY1-Antibody-N-term-Blocking-Peptide - BP2517a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

YY1 (1-414, His-tag) - AR51675PU-N from Acris Antibodies Category Protein Prices $1,010.00 Sizes 500 µg Source E. coli Species Human

YY1 (1-414, His-tag) - AR51675PU-S from Acris Antibodies Category Protein Prices $410.00 Sizes 100 µg Source E. coli Species Human

YY1 - H00007528-P01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

YY1 - H00007528-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

YY1 - H00007528-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

YY1 fusion protein - ag17792 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant YY1 protein - 31332 from ActiveMotif Category Protein Prices $390.00 Sizes 10 µg Source E. coli Species Human

Recombinant Human YY1, His-tagged - YY1-2674H from Creative Biomart Category Protein Source E. coli .

Recombinant Human YY1 - YY1-31565TH from Creative Biomart Category Protein Source Wheat germ Species Human

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