USP11

Gene Symbol USP11
Entrez Gene 8237
Alt Symbol UHX1
Species Human
Gene Type protein-coding
Description ubiquitin specific peptidase 11
Other Description deubiquitinating enzyme 11|ubiquitin carboxyl-terminal hydrolase 11|ubiquitin carboxyl-terminal hydrolase, X-linked|ubiquitin thioesterase 11|ubiquitin thiolesterase 11|ubiquitin-specific processing protease 11|ubiquitin-specific-processing protease 11
Swissprots Q8IUG6 P51784 B2RTX1 Q9BWE1
Accessions CBX47606 EAW59288 EAW59289 P51784 AB073597 BAC20463 AK055588 BAG51540 AK098394 AK294635 BAG57814 BC000350 AAH00350 BC063668 AAH63668 BC073960 BC140849 AAI40850 BQ022385 DQ581100 U44839 AAC50450 XM_005272674 XP_005272731 XM_011543988 XP_011542290 NM_004651 NP_004642
Function Protease that can remove conjugated ubiquitin from target proteins and polyubiquitin chains. Inhibits the degradation of target proteins by the proteasome. Plays a role in the regulation of pathways leading to NF-kappa-B activation. Plays a role in the regulation of DNA repair after double-stranded DNA breaks. {ECO:0000269|PubMed:15314155, ECO:0000269|PubMed:17897950, ECO:0000269|PubMed:18408009, ECO:0000269|PubMed:19874889, ECO:0000269|PubMed:20233726}.
Subcellular Location Nucleus. Cytoplasm. Note=Predominantly nuclear. Associates with chromatin.

USP11 (C-6) - sc-365528 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
USP11 (C-6): sc-365528. Western blot analysis of USP11 expression in Jurkat whole cell lysate.

USP11 (G-18) - sc-55799 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
USP11 (G-18): sc-55799. Western blot analysis of USP11 expression in Jurkat (A) and K-562 (B) whole cell lysates.

USP11 (P-18) - sc-55801 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
USP11 (P-18): sc-55801. Western blot analysis of USP11 expression in non-transfected: sc-117752 (A) and mouse USP11 transfected: sc-124490 (B) 293T whole cell lysates.

USP11 (H-80) - sc-134928 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
USP11 (H-80): sc-134928. Western blot analysis of USP11 expression in non-transfected 293T: sc-117752 (A), mouse USP11 transfected 293T: sc-124490 (B) and Jurkat (C) whole cell lysates.

USP11 (S-18) - sc-55802 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-USP11 antibody - ab196816 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-USP11 antibody (ab196816) at 1/500 dilutionLane 1 : 293 cell extractLane 2 : 293 cell extract with synthesized peptide

Anti-USP11 antibody - ab5269 from Abcam

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-USP11 antibody [1220CT620.193.189] - ab191235 from Abcam

Prices $376.00
Sizes 400 µl
Host Mouse
Clonality Monoclonal
Clone 1220CT620.193.189
All lanes : Anti-USP11 antibody [1220CT620.193.189] (ab191235) at 1/1000 dilutionLane 1 : Jurkat cell line lysateLane 2 : HeLa cell line lysateLane 3 : LNCaP cell line lysateLysates/proteins at 35 µg per lane.SecondaryGoat anti-mouse IgG H&L(HRP) at 1/3000 dilution

Anti-USP11 antibody [EPR4345(2)] - ab133331 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4345(2)
All lanes : Anti-USP11 antibody [EPR4345(2)] (ab133331) at 1/1000 dilutionLane 1 : HeLa lysateLane 2 : Jurkat lysateLane 3 : Human fetal brain lysateLane 4 : 293T lysateLane 5 : Human testis lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-USP11 antibody [EPR4346] - ab109232 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4346
Flow cytometry analysis of 2% paraformaldehyde fixed Jurkat (Human T cell leukemia cells from peripheral blood) cells labeling USP11 with ab109232 at 1/570 dilution (red line). Secondary antibody used is a goat anti rabbit IgG (FITC) at 1/150 dilution. The isotype control is rabbit monoclonal IgG (black line). The unlabeled control is cells without incubation with primary and secondary antibodies (blue line).

Anti-USP11 antibody - C-terminal - ab71743 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-USP11 antibody - C-terminal (ab71743) at 1/100 dilution + 293 cell lysate at 12.5 µg

Anti-USP11 antibody - N-terminal - ab155664 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-USP11 antibody - N-terminal (ab155664) at 1/1000 dilution + HeLa S3 whole cell lysate at 30 µg

Anti-USP11 Antibody (N-Terminus, AP) - LS-C284135 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-USP11 Antibody (N-Terminus, APC) - LS-C284136 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-USP11 Antibody (N-Terminus, Biotin) - LS-C284137 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-USP11 Antibody (N-Terminus, FITC) - LS-C284138 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-USP11 Antibody (N-Terminus, Azide-free, HRP) - LS-C284139 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-USP11 Antibody (N-Terminus, PE) - LS-C284140 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-USP11 Antibody (N-Terminus, AP) - LS-C284141 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-USP11 Antibody (N-Terminus, APC) - LS-C284142 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-USP11 Antibody (N-Terminus, Biotin) - LS-C284143 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-USP11 Antibody (N-Terminus, FITC) - LS-C284144 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-USP11 Antibody (N-Terminus, PE) - LS-C284146 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-USP11 Antibody (aa951-963) - LS-C55650 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Antibody staining (1 ug/ml) of Jurkat lysate (RIPA buffer, 30 ug total protein per lane). Primary incubated for 1 hour. Detected by Western blot of chemiluminescence.

Anti-USP11 Antibody (N-Terminus, Azide-free, HRP) - LS-C284145 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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