| Gene Symbol | USP11 |
|---|---|
| Entrez Gene | 8237 |
| Alt Symbol | UHX1 |
| Species | Human |
| Gene Type | protein-coding |
| Description | ubiquitin specific peptidase 11 |
| Other Description | deubiquitinating enzyme 11|ubiquitin carboxyl-terminal hydrolase 11|ubiquitin carboxyl-terminal hydrolase, X-linked|ubiquitin thioesterase 11|ubiquitin thiolesterase 11|ubiquitin-specific processing protease 11|ubiquitin-specific-processing protease 11 |
| Swissprots | Q8IUG6 P51784 B2RTX1 Q9BWE1 |
| Accessions | CBX47606 EAW59288 EAW59289 P51784 AB073597 BAC20463 AK055588 BAG51540 AK098394 AK294635 BAG57814 BC000350 AAH00350 BC063668 AAH63668 BC073960 BC140849 AAI40850 BQ022385 DQ581100 U44839 AAC50450 XM_005272674 XP_005272731 XM_011543988 XP_011542290 NM_004651 NP_004642 |
| Function | Protease that can remove conjugated ubiquitin from target proteins and polyubiquitin chains. Inhibits the degradation of target proteins by the proteasome. Plays a role in the regulation of pathways leading to NF-kappa-B activation. Plays a role in the regulation of DNA repair after double-stranded DNA breaks. {ECO:0000269|PubMed:15314155, ECO:0000269|PubMed:17897950, ECO:0000269|PubMed:18408009, ECO:0000269|PubMed:19874889, ECO:0000269|PubMed:20233726}. |
| Subcellular Location | Nucleus. Cytoplasm. Note=Predominantly nuclear. Associates with chromatin. |
ubiquitin specific peptidase 11, ELISA Kit - MBS9327425 from MyBioSource
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ubiquitin specific peptidase 11, ELISA Kit - MBS9329483 from MyBioSource
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ubiquitin specific peptidase 11, ELISA Kit - MBS9326839 from MyBioSource
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Human USP11 ELISA Kit - E040307 from Biobool
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anti-USP11 antibody - ARG55818 from Arigo Biolaboratories
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anti-USP11 / UHX1 antibody - ARG63372 from Arigo Biolaboratories
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Ubiquitin carboxyl-terminal hydrolase 11, ELISA Kit - MBS285756 from MyBioSource
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