GRN

Gene Symbol GRN
Entrez Gene 2896
Alt Symbol CLN11, GEP, GP88, PCDGF, PEPI, PGRN
Species Human
Gene Type protein-coding
Description granulin
Other Description PC cell-derived growth factor|acrogranin|granulin-epithelin|granulins|proepithelin|progranulin
Swissprots Q9UCH0 D3DX55 P28799 Q53HQ8 Q540U8 P23784 P23781 P23783 Q53Y88 P23782 Q9H8S1 Q9BWE7
Accessions EAW51599 EAW51600 EAW51601 P28799 AF055008 AAC09359 AK000607 AK023348 BAB14535 AK222522 BAD96242 AK296090 BAG58844 AK303830 BAG64777 AY124489 AAM94026 BC000324 AAH00324 BC010577 AAH10577 BT006844 AAP35490 DC336362 M75161 AAA58617 X62320 CAA44196 XM_005257253 XP_005257310 NM_002087 NP_002078 NM_001012479
Function Granulins have possible cytokine-like activity. They may play a role in inflammation, wound repair, and tissue remodeling.
Subcellular Location Secreted.
Tissue Specificity In myelogenous leukemic cell lines of promonocytic, promyelocytic, and proerythroid lineage, in fibroblasts, and very strongly in epithelial cell lines. Present in inflammatory cells and bone marrow. Highest levels in kidney.

Active human Granulin full length protein - ab108590 from Abcam

Category Protein
Prices $302.00
Sizes 10 µg
Source HEK 293 cells
Species Human
Deglycosylation of ab108590. To examine deglycosylation of ab108590, 1 µg of ab108590 is denatured with 1X Glycoprotein Denaturing Buffer at 100°C for 10 minutes. After the addition of NP-40 and G7 Reaction Buffer, two-fold dilutions of PNGase F are added and the reaction mix is incubated for 1 or 3 hour at 37°C. Separation of reaction products are visualized by immunoblotting with antibody against anti-Human progranulin. Lane 1: Non-teated Lane 2: PNGase F, 1 hr Lane 3: PNGase F, 3 hr

Active human Granulin full length protein - ab191964 from Abcam

Category Protein
Prices $515.00
Sizes 100 µg
Source HEK 293 cells
Species Human
SDS-PAGE analysis of DTT-reduced ab191964 stained overnight with Coomassie Blue. DTT-reduced protein migrates as 90-100 kDa due to glycosylation.

Active human Granulin full length protein - ab113403 from Abcam

Category Protein
Prices $302.00
Sizes 10 µg
Source HEK 293 cells
Species Human

Active mouse Granulin full length protein - ab108573 from Abcam

Category Protein
Prices $302.00
Sizes 10 µg
Source HEK 293 cells
Species Mouse
Deglycosylation of ab108573. To examine deglycosylation of ab108573, 1µg of mouse progranulin (ab108573) was denatured with 1X Glycoprotein Denaturing Buffer at 100°C for 10 minutes. After the addition of NP-40 and G7 Reaction Buffer, two-fold dilutions of PNGase F were added and the reaction mix was incubated for 1 or 3 hour at 37°C. Separation of reaction products were visualized by immunoblotting with antibody against anti-mouse progranulin.

Human Granulin full length protein - ab108947 from Abcam

Category Protein
Source E. coli
Species Human

Mouse Granulin full length protein - ab134849 from Abcam

Category Protein
Source HEK 293 cells
Species Mouse

Rat Granulin full length protein - ab134859 from Abcam

Category Protein
Source HEK 293 cells
Species Rat
All lanes : Rat Granulin full length protein (ab134859) (Anti-FLAG-HRP antibody) Lane 1 : Granulin Lane 2 : Granulin denatured with 1X glycoprotein denaturing buffer at 100°C for 10 minutes. After the addition of NP- 40 and G7 reaction buffer, twofold dilutions of PNGase F are added and the reaction mix is incubated for 1 or 3 hours at 37°C. Lysates/proteins at 1 µg per lane.

GRN / Granulin Antibody Blocking Peptide - LS-E19691 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

GRN / Granulin Antibody Blocking Peptide - LS-E27830 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

GRN / Granulin Antibody Blocking Peptide - LS-E26880 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human Granulin Protein - H00002896-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human
SDS-Page: Granulin Partial Recombinant Protein [H00002896-Q01]

Recombinant Human Granulin Protein - H00002896-P01 from Novus Biologicals

Category Protein
Prices $319.00
Sizes 2 µg
Source Wheat Germ
Species Human

Recombinant Human Granulin Protein - H00002896-Q02 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

Recombinant Human Granulin Protein - NBP1-99540 from Novus Biologicals

Category Protein
Prices $225.00
Sizes 10 µg
Source HEK 293 cells
Species Human

Granulins blocking peptide - GTX88443-PEP from GeneTex

Category Peptide
Prices $239.00
Sizes 100 μg
Species Human

Recombinant Human Progranulin, CF - 2420-PG-050 from R&D Systems

Category Protein
Source Mouse myeloma cell line, NS0-derived, Thr18-Leu593, with a C-terminal 6-His tag

PGRN Protein (OPPA01505) - OPPA01505 from Aviva Systems Biology

Category Protein
Prices $100.00
Sizes 2 µg

Human PGRN protein - orb80550 from Biorbyt

Category Protein
Prices $170.00, $289.00, $1,139.00
Sizes 2 μg, 10 μg, 100 μg
Species Human

Human GRN His tag protein - orb83185 from Biorbyt

Category Protein
Prices $400.00, $612.00
Sizes 50 μg, 100 μg
Source Human
Species Human
SDS-PAGE analysis of human GRN His tag protein

Progranulin protein - 30R-2690 from Fitzgerald

Category Protein
Prices $290.00
Sizes 10 µg
Source 293 cells
Species Human

Human Granulin Protein - abx066905 from Abbexa

Category Protein
Source E.coli
Species Human

Human Granulin Protein - abx066904 from Abbexa

Category Protein
Source E.coli
Species Human

Human Granulin Protein - abx066903 from Abbexa

Category Protein
Source E.coli
Species Human

Granulin Peptide - AC21-1715-P from Abcore

Category Peptide
Prices $160.00
Sizes 100 µg

Granulin Peptide - AC21-2640-P from Abcore

Category Peptide
Prices $160.00
Sizes 100 µg
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