Recombinant Human Progranulin, CF

Name	Recombinant Human Progranulin, CF
Supplier	R&D Systems
Catalog	2420-PG-050
Category	Protein
Nature	Recombinant
Source	Mouse myeloma cell line, NS0-derived, Thr18-Leu593, with a C-terminal 6-His tag
Purity	>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
SwissProt/Accession	P28799
Gene	GRN
Supplier Page	Shop

Product References

Regulation of progranulin expression in human microglia and proteolysis of - Regulation of progranulin expression in human microglia and proteolysis of

Suh HS, Choi N, Tarassishin L, Lee SC. PLoS One. 2012;7(4):e35115.

Widespread potential for growth-factor-driven resistance to anticancer kinase - Widespread potential for growth-factor-driven resistance to anticancer kinase

Wilson TR, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, Peng J, Lin E, Wang Y, Sosman J, Ribas A, Li J, Moffat J, Sutherlin DP, Koeppen H, Merchant M, Neve R, Settleman J. Nature. 2012 Jul 26;487(7408):505-9.

Human tumors instigate granulin-expressing hematopoietic cells that promote - Human tumors instigate granulin-expressing hematopoietic cells that promote

Elkabets M, Gifford AM, Scheel C, Nilsson B, Reinhardt F, Bray MA, Carpenter AE, Jirstrom K, Magnusson K, Ebert BL, Ponten F, Weinberg RA, McAllister SS. J Clin Invest. 2011 Feb;121(2):784-99.

Serum biomarker for progranulin-associated frontotemporal lobar degeneration. - Serum biomarker for progranulin-associated frontotemporal lobar degeneration.

Sleegers K, Brouwers N, Van Damme P, Engelborghs S, Gijselinck I, van der Zee J, Peeters K, Mattheijssens M, Cruts M, Vandenberghe R, De Deyn PP, Robberecht W, Van Broeckhoven C. Ann Neurol. 2009 May;65(5):603-9.

Progranulin functions as a neurotrophic factor to regulate neurite outgrowth and - Progranulin functions as a neurotrophic factor to regulate neurite outgrowth and

Van Damme P, Van Hoecke A, Lambrechts D, Vanacker P, Bogaert E, van Swieten J, Carmeliet P, Van Den Bosch L, Robberecht W. J Cell Biol. 2008 Apr 7;181(1):37-41.