Gene Symbol | SERPINB1 |
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Entrez Gene | 1992 |
Alt Symbol | EI, ELANH2, HEL57, LEI, M/NEI, MNEI, PI-2, PI2 |
Species | Human |
Gene Type | protein-coding |
Description | serpin peptidase inhibitor, clade B (ovalbumin), member 1 |
Other Description | epididymis luminal protein 57|leukocyte elastase inhibitor|peptidase inhibitor 2|protease inhibitor 2 (anti-elastase), monocyte/neutrophil derived|serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 1 |
Swissprots | P30740 Q9UDF8 B4DNT0 Q53FB9 Q5W0E1 A8K5L2 |
Accessions | AAC31394 EAW55089 EAW55090 P30740 AK223370 BAD97090 AK291327 BAF84016 AK298044 BAG60342 AK304641 BAG65420 AK309765 AK312973 AW451326 BC009015 AAH09015 BI521531 BM785367 BM823453 BT006928 AAP35574 BU942473 EU794624 ACJ13678 M93056 XM_011514333 XP_011512635 XM_011514334 XP_011512636 XM_011514335 XP_011512637 NM_030666 NP_109591 NR_073111 NR_073112 |
Function | Regulates the activity of the neutrophil proteases elastase, cathepsin G, proteinase-3, chymase, chymotrypsin, and kallikrein-3. Also functions as a potent intracellular inhibitor of granzyme H. {ECO:0000269|PubMed:11747453}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Cytoplasmic granule {ECO:0000269|PubMed:23269243}. |
Top Pathways | Amoebiasis |
SerpinB1 (A-17) - sc-34305 from Santa Cruz Biotechnology
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SerpinB1 (H-40) - sc-66957 from Santa Cruz Biotechnology
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SerpinB1/B1a (K-17) - sc-34304 from Santa Cruz Biotechnology
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Anti-SERPINB1 antibody - ab47731 from Abcam
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Anti-SERPINB1 antibody - ab92907 from Abcam
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Anti-SERPINB1 antibody - ab124083 from Abcam
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Anti-SERPINB1 antibody - ab137523 from Abcam
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Anti-SERPINB1 antibody [EPR13299] - N-terminal - ab190357 from Abcam
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Anti-SERPINB1 antibody [EPR13305(B)] - ab181084 from Abcam
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Anti-SERPINB1 Antibody (clone 3B4) - LS-C174603 from LifeSpan Bioscience
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Anti-SERPINB1 Antibody (aa77-306, clone 2B4) - LS-C336913 from LifeSpan Bioscience
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Anti-SERPINB1 Antibody (clone 4B3) - LS-C175122 from LifeSpan Bioscience
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Anti-SERPINB1 Antibody - LS-C184001 from LifeSpan Bioscience
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Anti-SERPINB1 Antibody (aa168-196, AP) - LS-C269030 from LifeSpan Bioscience
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Anti-SERPINB1 Antibody (aa168-196, APC) - LS-C269031 from LifeSpan Bioscience
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Anti-SERPINB1 Antibody (aa168-196, FITC) - LS-C269033 from LifeSpan Bioscience
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Anti-SERPINB1 Antibody (aa168-196, Biotin) - LS-C269032 from LifeSpan Bioscience
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Anti-SERPINB1 Antibody (aa168-196) - LS-C168985 from LifeSpan Bioscience
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Anti-SERPINB1 Antibody (aa215-264) - LS-C111396 from LifeSpan Bioscience
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Anti-SERPINB1 Antibody (aa168-196, Azide-free, HRP) - LS-C269034 from LifeSpan Bioscience
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Anti-SERPINB1 Antibody (aa168-196, PE) - LS-C269035 from LifeSpan Bioscience
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Anti-SERPINB1 Antibody (aa167-196) - LS-C325013 from LifeSpan Bioscience
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Anti-SERPINB1 Antibody - LS-C342004 from LifeSpan Bioscience
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Anti-SERPINB1 Antibody (clone 4A7) - LS-C197123 from LifeSpan Bioscience
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Anti-SERPINB1 Antibody (Internal) - LS-C345722 from LifeSpan Bioscience
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