Gene Symbol | SERPINB1 |
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Entrez Gene | 1992 |
Alt Symbol | EI, ELANH2, HEL57, LEI, M/NEI, MNEI, PI-2, PI2 |
Species | Human |
Gene Type | protein-coding |
Description | serpin peptidase inhibitor, clade B (ovalbumin), member 1 |
Other Description | epididymis luminal protein 57|leukocyte elastase inhibitor|peptidase inhibitor 2|protease inhibitor 2 (anti-elastase), monocyte/neutrophil derived|serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 1 |
Swissprots | P30740 Q9UDF8 B4DNT0 Q53FB9 Q5W0E1 A8K5L2 |
Accessions | AAC31394 EAW55089 EAW55090 P30740 AK223370 BAD97090 AK291327 BAF84016 AK298044 BAG60342 AK304641 BAG65420 AK309765 AK312973 AW451326 BC009015 AAH09015 BI521531 BM785367 BM823453 BT006928 AAP35574 BU942473 EU794624 ACJ13678 M93056 XM_011514333 XP_011512635 XM_011514334 XP_011512636 XM_011514335 XP_011512637 NM_030666 NP_109591 NR_073111 NR_073112 |
Function | Regulates the activity of the neutrophil proteases elastase, cathepsin G, proteinase-3, chymase, chymotrypsin, and kallikrein-3. Also functions as a potent intracellular inhibitor of granzyme H. {ECO:0000269|PubMed:11747453}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Cytoplasmic granule {ECO:0000269|PubMed:23269243}. |
Top Pathways | Amoebiasis |
SERPINB1-Over-expression-Lysate - LY12540a from Abgent, a WuXi AppTec company
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SERPINB1 293T Cell Transient Overexpression Lysate(Denatured) - H00001992-T01 from Acris Antibodies
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SERPINB1 293 Cell Lysate - 405459 from ABBIOTEC
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SERPINB1 Overexpression Lysate (Denatured) - H00001992-T01 from Novus Biologicals
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SERPINB1 Overexpression Lysate (Native) - NBL1-15842 from Novus Biologicals
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SERPINB1 Over-expression Lysate Product - GWB-8C62CC from Genway Biotech
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Human SerpinB1 / ELANH2 Insect Cell Lysate (WB positive control) - 12588-H08BL-300 from Sino Biological
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Human SerpinB1 Baculovirus-Insect Cells Transfected Lysate (positive control) (denatured) - orb175048 from Biorbyt
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SERPINB1 Overexpression Lysate (Denatured) - H00001992-T02 from Novus Biologicals
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Panoply™ Human SERPINB1 Knockdown Stable Cell Line - CSC-DC014044 from Creative biogene
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Human SERPINB1 Knockout Cell Line-HeLa - CSC-RT1058 from Creative biogene
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SERPINB1 KO Cell Lysate-HeLa - CLKO-0548 from Creative biogene
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