Gene Symbol | SERPINB1 |
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Entrez Gene | 1992 |
Alt Symbol | EI, ELANH2, HEL57, LEI, M/NEI, MNEI, PI-2, PI2 |
Species | Human |
Gene Type | protein-coding |
Description | serpin peptidase inhibitor, clade B (ovalbumin), member 1 |
Other Description | epididymis luminal protein 57|leukocyte elastase inhibitor|peptidase inhibitor 2|protease inhibitor 2 (anti-elastase), monocyte/neutrophil derived|serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 1 |
Swissprots | P30740 Q9UDF8 B4DNT0 Q53FB9 Q5W0E1 A8K5L2 |
Accessions | AAC31394 EAW55089 EAW55090 P30740 AK223370 BAD97090 AK291327 BAF84016 AK298044 BAG60342 AK304641 BAG65420 AK309765 AK312973 AW451326 BC009015 AAH09015 BI521531 BM785367 BM823453 BT006928 AAP35574 BU942473 EU794624 ACJ13678 M93056 XM_011514333 XP_011512635 XM_011514334 XP_011512636 XM_011514335 XP_011512637 NM_030666 NP_109591 NR_073111 NR_073112 |
Function | Regulates the activity of the neutrophil proteases elastase, cathepsin G, proteinase-3, chymase, chymotrypsin, and kallikrein-3. Also functions as a potent intracellular inhibitor of granzyme H. {ECO:0000269|PubMed:11747453}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Cytoplasmic granule {ECO:0000269|PubMed:23269243}. |
Top Pathways | Amoebiasis |
Human SERPINB1 full length protein - ab114774 from Abcam
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Human SERPINB1 protein fragment - ab114775 from Abcam
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SERPINB1 Antibody Blocking Peptide - LS-E3942 from LifeSpan Bioscience
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SERPINB1 Antibody Blocking Peptide - LS-E18849 from LifeSpan Bioscience
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Recombinant Human SERPINB1 Protein - H00001992-Q01 from Novus Biologicals
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Recombinant Human SERPINB1 Protein - H00001992-P01 from Novus Biologicals
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SERPINB1-Antibody-Center-Blocking-Peptide - BP16141c from Abgent, a WuXi AppTec company
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Human SERPINB1 protein - orb244532 from Biorbyt
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Human SerpinB1 His tag protein - orb84445 from Biorbyt
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SERPINB1 Blocking Peptide - 33R-8251 from Fitzgerald
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SERPINB1 - H00001992-P01-10 from Acris Antibodies
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SERPINB1 - H00001992-P01-25 from Acris Antibodies
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SERPINB1 - H00001992-Q01-10 from Acris Antibodies
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SERPINB1 - H00001992-Q01-25 from Acris Antibodies
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Recombinant Human SerpinB1, His tagged - SerpinB1-3981H from Creative Biomart
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Recombinant Human SERPINB1 - SERPINB1-31161TH from Creative Biomart
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Recombinant Human SERPINB1 - SERPINB1-31187TH from Creative Biomart
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Recombinant Leukocyte Elastase Inhibitor (LEI) - RPD387Hu01 from Uscn Life Science Inc.
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Recombinant Leukocyte Elastase Inhibitor (LEI) - RPD387Mu01 from Uscn Life Science Inc.
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Recombinant Leukocyte Elastase Inhibitor (LEI) - RPD387Mu02 from Uscn Life Science Inc.
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Human SerpinB1 / ELANH2 Protein (His Tag) - 12588-H08B-20 from Sino Biological
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Recombinant Leukocyte Elastase Inhibitor (LEI) - RPD387Hu01 from Cloud-clone
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Recombinant Human Leukocyte elastase inhibitor(SERPINB1) - CSB-YP021065HU CSB-BP021065HU CSB-MP021065HU from Cusabio
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Recombinant human Leukocyte elastase inhibitor - CSB-EP021065HU from Cusabio
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Leukocyte Elastase Inhibitor Protein (Recombinant) - abx166972 from Abbexa
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