S100B

Gene Symbol	S100B
Entrez Gene	6285
Alt Symbol	NEF, S100, S100-B, S100beta
Species	Human
Gene Type	protein-coding
Description	S100 calcium binding protein B
Other Description	S-100 calcium-binding protein, beta chain|S-100 protein subunit beta|S100 calcium-binding protein, beta (neural)|protein S100-B
Swissprots	P04271 D3DSN6
Accessions	AAA60367 EAX09267 EAX09268 EAX09269 EAX09270 P04271 AA310307 BC001766 AAH01766 BC041935 CR542123 CAG46920 DQ892491 ABM83417 EB386131 EU176695 ABW03496 NM_006272 NP_006263
Function	Weakly binds calcium but binds zinc very tightly- distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity. {ECO:0000269|PubMed:20351179, ECO:0000269|PubMed:22399290}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:9925766}. Nucleus {ECO:0000269|PubMed:9925766}.
Tissue Specificity	Although predominant among the water-soluble brain proteins, S100 is also found in a variety of other tissues.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human S100B gene - orb90781 from Biorbyt Prices $255.00 Sizes 10 μg Species Human

Human-S100B-cDNA-Clone - DC00816 from Abgent, a WuXi AppTec company Prices $124.20 Sizes 10 µg Species Human Accession BC001766

S100B - MBS1270359 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC001766

Human S100B ORF clone(NM_006272.2) - CDCL186052 from Creative Biomart Species Human Accession NM_006272.2

Human S100B ORF Clone(NM_006272.2) - CDCL174476 from Creative Biomart Species Human Accession NM_006272.2

Human S100B Gene ORF cDNA clone in cloning vector - HG10181-M from Sino Biological Species Human

Human S100B Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG10181-ANG from Sino Biological Species Human

Human S100B Gene ORF cDNA clone expression plasmid, C-His tag - HG10181-CH from Sino Biological Species Human

Human S100B Gene ORF cDNA clone expression plasmid, N-Flag tag - HG10181-NF from Sino Biological Species Human

Human S100B Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10181-CF from Sino Biological Species Human

Human S100B Gene ORF cDNA clone expression plasmid, N-Myc tag - HG10181-NM from Sino Biological Species Human

Human S100B Gene ORF cDNA clone expression plasmid, N-HA tag - HG10181-NY from Sino Biological Species Human

Human S100B Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG10181-ACG from Sino Biological Species Human

Human S100B Gene ORF cDNA clone expression plasmid, C-Myc tag - HG10181-CM from Sino Biological Species Human

Human S100B Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10181-M-F from Sino Biological Species Human

Human S100B Gene cDNA Clone (full-length ORF Clone), expression ready, untagged - HG10181-M-N from Sino Biological Species Human Accession NM_006272.2

Human S100B Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG10181-ACR from Sino Biological Species Human

Human S100B Gene ORF cDNA clone expression plasmid, N-His tag - HG10181-NH from Sino Biological Species Human

Human S100B Gene ORF cDNA clone expression plasmid - HG10181-UT from Sino Biological Species Human

Human S100B Gene ORF cDNA clone expression plasmid, C-HA tag - HG10181-CY from Sino Biological Species Human

Human S100B ORF clone(NM_006272.2) - CDCL186052 from Creative biogene Species Human

Human S100B ORF Clone (BC001766) - CDCS412639 from Creative biogene Species Human Accession P04271

Human S100B Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG10181-ANR from Sino Biological Species Human

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