S100B

Gene Symbol	S100B
Entrez Gene	6285
Alt Symbol	NEF, S100, S100-B, S100beta
Species	Human
Gene Type	protein-coding
Description	S100 calcium binding protein B
Other Description	S-100 calcium-binding protein, beta chain|S-100 protein subunit beta|S100 calcium-binding protein, beta (neural)|protein S100-B
Swissprots	P04271 D3DSN6
Accessions	AAA60367 EAX09267 EAX09268 EAX09269 EAX09270 P04271 AA310307 BC001766 AAH01766 BC041935 CR542123 CAG46920 DQ892491 ABM83417 EB386131 EU176695 ABW03496 NM_006272 NP_006263
Function	Weakly binds calcium but binds zinc very tightly- distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity. {ECO:0000269|PubMed:20351179, ECO:0000269|PubMed:22399290}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:9925766}. Nucleus {ECO:0000269|PubMed:9925766}.
Tissue Specificity	Although predominant among the water-soluble brain proteins, S100 is also found in a variety of other tissues.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Rat S100B / S100 Beta ELISA Kit (Sandwich ELISA) - LS-F5632 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 31.2 pg/ml Range 0.156-10 ng/ml

Human S100B / S100 Beta ELISA Kit (Sandwich ELISA) - LS-F5631 from LifeSpan Bioscience Category ELISA Kit Prices $650.00 Sizes 1 plate Sensitivity 0.156 ng/ml Range 0.156-10 ng/ml

Mouse S100B / S100 Beta ELISA Kit (Sandwich ELISA) - LS-F5980 from LifeSpan Bioscience Category ELISA Kit Prices $670.00 Sizes 1 plate Sensitivity 31.25 pg/ml Range 0.156-10 ng/ml

Human S100B / S100 Beta ELISA Kit (Sandwich ELISA) - LS-F12528 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity 15.6 pg/ml Range 0.156-10 ng/ml

Mouse S100B / S100 Beta ELISA Kit (Sandwich ELISA) - LS-F12530 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 15.6 pg/ml Range 0.156-10 ng/ml

S100 ELISA kit - 55R-70885 from Fitzgerald Category ELISA Kit Prices $1,795.00 Sizes 96 wells

Human S100 ELISA kit - orb196482 from Biorbyt Category ELISA Kit Prices $655.00 Sizes 96 test

Protein S100-B, S100B, Human, ELISA Kit - E0567h from ARP American Research Products Category ELISA Kit Prices $476.00 Sizes 96 t Range 15.6-1000 pg/mL

Soluble Protein-100, S-100, Human, ELISA Kit - E-EL-H0927 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 0.094 Range 0.156-10ng/mL

S100 (S100 Calcium Binding Protein), Human, ELISA Kit - E-EL-H0162 from ARP American Research Products Category ELISA Kit Prices $617.40 Sizes 96 t

S100 Calcium Binding Protein B (S100B), Human, ELISA Kit - SEA567Hu from ARP American Research Products Category ELISA Kit Prices $650.00 Sizes 96 t Sensitivity 0.056ng/mL Range 0.156-10ng/mL

S100 Calcium Binding Protein B, S100B, Human, ELISA Kit - E-EL-H1297 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 18.75 Range 31.25-2000pg/mL

Soluble protein-100, S-100, Human, ELISA Kit - CSB-E08067h from ARP American Research Products Category ELISA Kit Prices $565.00, $835.00, $837.00, $839.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 0.04 ng/ml Range 0.16 ng/ml-10 ng/ml

Soluble protein-100B, S-100B, Human, ELISA Kit - CSB-E08065h from ARP American Research Products Category ELISA Kit Prices $565.00, $835.00, $837.00, $839.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 1.17 pg/ml Range 4.7 pg/ml-300 pg/ml

Soluble protein-100, S-100, Mouse, ELISA Kit - E-EL-M1082 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

S100 (S100 Calcium Binding Protein) , Mouse, ELISA Kit - E-EL-M1034 from ARP American Research Products Category ELISA Kit Prices $617.40 Sizes 96 t

S100 Calcium Binding Protein B, S100B, Mouse, ELISA Kit - E-EL-M1033 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 46.875 Range 78.125-5000pg/mL

Soluble Protein-100, S-100, Rat, ELISA Kit - E-EL-R0903 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 18.75 Range 31.25-2000pg/mL

S100 (S100 Calcium Binding Protein) , Rat, ELISA Kit - E-EL-R0869 from ARP American Research Products Category ELISA Kit Prices $617.40 Sizes 96 t

S100 Calcium Binding Protein B, S100B, Rat, ELISA Kit - E-EL-R0868 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 37.5 Range 62.5-4000pg/mL

S-100 (Soluble Protein-100), Rabbit, ELISA Kit - E-EL-RB0080 from ARP American Research Products Category ELISA Kit Prices $773.00 Sizes 96 t

S100 (S100 Calcium Binding Protein), Rabbit, ELISA Kit - E-EL-RB1353 from ARP American Research Products Category ELISA Kit Prices $773.00 Sizes 96 t

S100 Calcium Binding Protein B, S100B, Rabbit, ELISA Kit - E-EL-RB0043 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 9.375 Range 15.625-1000pg/mL

S-100 (Soluble Protein-100), Chicken, ELISA Kit - E-EL-Ch1059 from ARP American Research Products Category ELISA Kit Prices $773.00 Sizes 96 t

S100 (S100 Calcium Binding Protein), Chicken, ELISA Kit - E-EL-Ch1863 from ARP American Research Products Category ELISA Kit Prices $773.00 Sizes 96 t

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