SOST

Gene Symbol	SOST
Entrez Gene	50964
Alt Symbol	CDD, SOST1, VBCH
Species	Human
Gene Type	protein-coding
Description	sclerostin
Other Description	-
Swissprots	Q9BQB4 Q495N9
Accessions	AAK13451 CAI46877 CEF39438 EAW51669 Q9BQB4 AF170491 AAQ13601 AF184211 AAQ13694 AF326739 AAK13454 AF331844 AAK16158 AY358203 AAQ88570 AY358627 AAQ88990 BC101086 AAI01087 BC101087 AAI01088 BC101088 AAI01089 BC101089 AAI01090 NM_025237 NP_079513
Function	Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation. {ECO:0000269|PubMed:15908424}.
Subcellular Location	Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:20551380}.
Tissue Specificity	Widely expressed at low levels with highest levels in bone, cartilage, kidney, liver, bone marrow and primary osteoblasts differentiated for 21 days. Detected in the subendothelial layer of the aortic intima (at protein level). {ECO:0000269|PubMed:20551380}.
Top Pathways	Wnt signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-SOST-cDNA-Clone - DC09199 from Abgent, a WuXi AppTec company Prices $287.55 Sizes 10 µg Species Human Accession BC101086

SOST - MBS1271146 from MyBioSource Species Human Accession BC101086

Human SOST cDNA clone(NM_025237.2) - CDFG005023 from Creative Biomart Species Human Accession NM_025237.2

human SOST ORF clone - CDCH084530 from Creative Biomart Species Human Accession NM_025237

human SOST ORF clone - CDCH084531 from Creative Biomart Species Human Accession NM_025237

human SOST ORF clone - CDCH084532 from Creative Biomart Species Human Accession NM_025237

human SOST ORF clone - CDCH084533 from Creative Biomart Species Human Accession NM_025237

Human SOST ORF Clone(NM_025237.2) - CDCR310382 from Creative Biomart Species Human Accession NM_025237.2

Human SOST ORF Clone(NM_025237.2) - CDCR310383 from Creative Biomart Species Human Accession NM_025237.2

Human SOST ORF Clone(NM_025237.2) - CDCR310384 from Creative Biomart Species Human Accession NM_025237.2

Human SOST ORF Clone(NM_025237.2) - CDCL176671 from Creative Biomart Species Human Accession NM_025237.2

Human SOST ORF Clone(NM_025237.2) - CDCR310382 from Creative biogene Species Human

Human SOST ORF Clone (BC101086) - CDCS415942 from Creative biogene Species Human Accession Q9BQB4

Human SOST cDNA Clone(NM_025237.2) - CDFG005023 from Creative biogene Species Human

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