SOST

Gene Symbol SOST
Entrez Gene 50964
Alt Symbol CDD, SOST1, VBCH
Species Human
Gene Type protein-coding
Description sclerostin
Other Description -
Swissprots Q9BQB4 Q495N9
Accessions AAK13451 CAI46877 CEF39438 EAW51669 Q9BQB4 AF170491 AAQ13601 AF184211 AAQ13694 AF326739 AAK13454 AF331844 AAK16158 AY358203 AAQ88570 AY358627 AAQ88990 BC101086 AAI01087 BC101087 AAI01088 BC101088 AAI01089 BC101089 AAI01090 NM_025237 NP_079513
Function Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation. {ECO:0000269|PubMed:15908424}.
Subcellular Location Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:20551380}.
Tissue Specificity Widely expressed at low levels with highest levels in bone, cartilage, kidney, liver, bone marrow and primary osteoblasts differentiated for 21 days. Detected in the subendothelial layer of the aortic intima (at protein level). {ECO:0000269|PubMed:20551380}.
Top Pathways Wnt signaling pathway

SOST-Over-expression-Lysate - LY12064a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag SOST (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the SOST gene

SOST overexpression lysate - LY403063 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

SOST 293 Cell Lysate - 402667 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

SOST/Sclerostin Overexpression Lysate (Native) - NBL1-16341 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: Sclerostin Overexpression Lysate (Adult Normal) [NBL1-16341] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Sclerostin.

SOST Over-expression Lysate Product - GWB-724279 from Genway Biotech

Category Cell Lysate
Prices $445.00
Sizes 100 µg
Species Human

Human Sclerostin / SOST HEK293 Cell Lysate (WB positive control) - 10593-H07HL-300 from Sino Biological

Category Cell Lysate
Prices $195.00
Sizes 300 µg
Species Human

Human SOST Human Cells Transfected Lysate (positive control) (denatured) - orb173011 from Biorbyt

Category Cell Lysate
Prices $604.00
Sizes 300 μg
Species Human

Panoply™ Human SOST Knockdown Stable Cell Line - CSC-DC014901 from Creative biogene

Category Cell Line
Species Human
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