SOST

Gene Symbol	SOST
Entrez Gene	50964
Alt Symbol	CDD, SOST1, VBCH
Species	Human
Gene Type	protein-coding
Description	sclerostin
Other Description	-
Swissprots	Q9BQB4 Q495N9
Accessions	AAK13451 CAI46877 CEF39438 EAW51669 Q9BQB4 AF170491 AAQ13601 AF184211 AAQ13694 AF326739 AAK13454 AF331844 AAK16158 AY358203 AAQ88570 AY358627 AAQ88990 BC101086 AAI01087 BC101087 AAI01088 BC101088 AAI01089 BC101089 AAI01090 NM_025237 NP_079513
Function	Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation. {ECO:0000269|PubMed:15908424}.
Subcellular Location	Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:20551380}.
Tissue Specificity	Widely expressed at low levels with highest levels in bone, cartilage, kidney, liver, bone marrow and primary osteoblasts differentiated for 21 days. Detected in the subendothelial layer of the aortic intima (at protein level). {ECO:0000269|PubMed:20551380}.
Top Pathways	Wnt signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

SOST Human ELISA Kit - ab155440 from Abcam Category ELISA Kit Prices $531.00 Sizes 1 x 96 tests Sensitivity < 15 pg/ml Range 0.017 ng/ml - 10 ng/ml

Mouse SOST / Sclerostin ELISA Kit (Sandwich ELISA) - LS-F2864 from LifeSpan Bioscience Category ELISA Kit Prices $570.00 Sizes 1 plate Sensitivity 15.6 pg/ml Range 40.96-4000 pg/ml

Human SOST / Sclerostin ELISA Kit (Sandwich ELISA) - LS-F5928 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.113 ng/ml Range 40.96-4000 pg/ml

Rat SOST / Sclerostin ELISA Kit (Sandwich ELISA) - LS-F6287 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 78.13 pg/ml Range 40.96-4000 pg/ml

Mouse SOST / Sclerostin ELISA Kit (Sandwich ELISA) - LS-F6683 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 2.79 pg/ml Range 40.96-4000 pg/ml

Human SOST / Sclerostin ELISA Kit (Sandwich ELISA) - LS-F187 from LifeSpan Bioscience Category ELISA Kit Prices $670.00, $1,190.00, $2,570.00 Sizes 1 plate, 2 plate, 5 plate Sensitivity 40.96 pg/ml Range 40.96-4000 pg/ml

Human SOST / Sclerostin ELISA Kit (Sandwich ELISA) - LS-F12642 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity 0.312 Range 40.96-4000 pg/ml

Rat SOST / Sclerostin ELISA Kit (Sandwich ELISA) - LS-F12641 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity 0.312 Range 40.96-4000 pg/ml

Human SOST ELISA Kit - RAB0435 from Sigma-Aldrich Category ELISA Kit Prices $666.00 Sizes 1 kt

Mouse/Rat SOST/Sclerostin Quantikine ELISA Kit - MSST00 from R&D Systems Category ELISA Kit Prices $479.00 Sizes 1 kit Sensitivity 4.17 pg/mL Range 15.6 - 1,000 pg/mL

Human SOST/Sclerostin DuoSet ELISA - DY1406 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 62.50 - 4,000 pg/mL

Human SOST/Sclerostin Quantikine ELISA Kit - DSST00 from R&D Systems Category ELISA Kit Prices $519.00 Sizes 1 kit Sensitivity 3.8 pg/mL Range 0.0 - 0 Not Assigned, 31.3 - 2,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma)

Quantikine Immunoassay Control Set797 Human SOST/Sclerostin - QC159 from R&D Systems Category ELISA Kit Prices $125.00 Sizes 1 each

Mouse SOST/Sclerostin DuoSet ELISA - DY1589-05 from R&D Systems Category ELISA Kit Prices $299.00 Sizes 1 kit (for 5 Plates) Range 31.20 - 2,000 pg/mL

Sclerostin (SOST), Human, ELISA Kit - CSB-E13146h from ARP American Research Products Category ELISA Kit Prices $550.00, $790.00, $791.00, $794.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 0.39 pg/ml Range 1.56 pg/ml-100 pg/ml

Sclerostin (SOST), Human, ELISA Kit - SEC864Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.122ng/mL Range 0.312-20ng/mL.

Sclerostin, Human, ELISA Kit - E01S0207 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 0.1ng/ml Range 1.0-25ng/ml

Sclerostin, SOST, Human, ELISA Kit - E1713h from ARP American Research Products Category ELISA Kit Prices $476.00 Sizes 96 t Range 0.312-20 ng/mL

Sclerostin, SOST, Human, ELISA Kit - E-EL-H1544 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 37.5 Range 62.5-4000pg/mL

Human SOST ELISA - ELH-SOST from RayBiotech Category ELISA Kit Prices $390.00, $702.00, $1,561.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit Sensitivity 40 pg/ml Range 15 pg/ml - 10000 pg/ml

Human SOST ELISA Kit - HS0214 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine SOST ELISA Kit - AS0214 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Human SOST ELISA Kit - DEIA577 from Creative Diagnostics Category ELISA Kit

Human Sclerostin (SOST) ELISA KIT - DEIA7082 from Creative Diagnostics Category ELISA Kit Sensitivity 15 pg/mL Range 125-4000 pg/mL

Human SOST(Sclerostin) ELISA Kit - E-EL-H1544 from Elabscience Category ELISA Kit Sensitivity 37.50 pg/mL Range 62.50—4000 pg/mL

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