Gene Symbol | TBPL1 |
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Entrez Gene | 9519 |
Alt Symbol | MGC:8389, MGC:9620, STUD, TLF, TLP, TRF2 |
Species | Human |
Gene Type | protein-coding |
Description | TBP-like 1 |
Other Description | 21-kDA TBP-like protein|TATA box-binding protein-like protein 1|TATA box-binding protein-related factor 2|TBP-related factor 2|TBP-related protein|second TBP of unique DNA protein |
Swissprots | Q9BWD5 A8K8F5 P62380 |
Accessions | EAW47995 EAW47996 EAW47997 EAW47998 P62380 AB020881 BAA75218 AF130312 AAD24800 AF136570 AAD28785 AI187713 AK292320 BAF85009 AK313645 BAG36402 BC000381 AAH00381 BC017559 AAH17559 BI560657 BI828497 EU446932 ABZ92461 R42082 NM_001253676 NP_001240605 NM_004865 NP_004856 |
Function | Part of a specialized transcription system that mediates the transcription of most ribosomal proteins through the 5'-TCT-3' motif which is a core promoter element at these genes. Seems to also mediate the transcription of NF1. Does not bind the TATA box. {ECO:0000269|PubMed:10082669, ECO:0000269|PubMed:10220372, ECO:0000269|PubMed:15767669, ECO:0000269|PubMed:24958592}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. |
Tissue Specificity | Ubiquitously expressed, with highest levels in the testis and ovary. {ECO:0000269|PubMed:10082669, ECO:0000269|PubMed:17570761}. |
Top Pathways | Huntington's disease, HTLV-I infection, Herpes simplex infection, Viral carcinogenesis, Epstein-Barr virus infection |
TLF (C-8) - sc-514059 from Santa Cruz Biotechnology
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TLF (C-16) - sc-10105 from Santa Cruz Biotechnology
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TLF (H-110) - sc-366250 from Santa Cruz Biotechnology
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TLF (N-15) - sc-10102 from Santa Cruz Biotechnology
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Anti-TBP like protein TLP [EPR16048] antibody - ab191391 from Abcam
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Anti-TBP like protein TLP antibody - ab85064 from Abcam
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Anti-TBP like protein TLP antibody - ab3605 from Abcam
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Anti-TBPL1 / TRF2 Antibody (aa173-186) - LS-C55566 from LifeSpan Bioscience
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Anti-TBPL1 / TRF2 Antibody (aa88-137) - LS-C30591 from LifeSpan Bioscience
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Anti-TBPL1 / TRF2 Antibody (Internal) - LS-C137074 from LifeSpan Bioscience
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TBP like protein TLP Antibody - NBP1-31133 from Novus Biologicals
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TBP like protein TLP Antibody - NB100-1101 from Novus Biologicals
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TBP like protein TLP Antibody - H00009519-A01 from Novus Biologicals
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Anti-TBPL1 antibody produced in rabbit - AV35751 from Sigma-Aldrich
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Anti-TBPL1 antibody produced in rabbit - SAB2700856 from Sigma-Aldrich
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Anti-TBPL1/TLF/TRF2 antibody produced in goat - SAB2501020 from Sigma-Aldrich
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TBPL1 antibody - middle region (ARP35751_T100) - ARP35751_T100 from Aviva Systems Biology
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TBPL1--TLF--TRF2-Antibody - AF2070a from Abgent, a WuXi AppTec company
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TBPL1 antibody - orb77297 from Biorbyt
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Goat Anti-TBPL1 / TLF / TRF2 Antibody (OAEB01914) - OAEB01914 from Aviva Systems Biology
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TBPL1 Polyclonal Antibody - A7575 from ABclonal
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TBPL1 antibody - 70R-20721 from Fitzgerald
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TBPL1 Antibody - abx037496 from Abbexa
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TBPL1 antibody - 12258-1-AP from Acris Antibodies
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TBPL1 antibody - H00009519-A01 from Acris Antibodies
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