Gene Symbol | TBPL1 |
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Entrez Gene | 9519 |
Alt Symbol | MGC:8389, MGC:9620, STUD, TLF, TLP, TRF2 |
Species | Human |
Gene Type | protein-coding |
Description | TBP-like 1 |
Other Description | 21-kDA TBP-like protein|TATA box-binding protein-like protein 1|TATA box-binding protein-related factor 2|TBP-related factor 2|TBP-related protein|second TBP of unique DNA protein |
Swissprots | Q9BWD5 A8K8F5 P62380 |
Accessions | EAW47995 EAW47996 EAW47997 EAW47998 P62380 AB020881 BAA75218 AF130312 AAD24800 AF136570 AAD28785 AI187713 AK292320 BAF85009 AK313645 BAG36402 BC000381 AAH00381 BC017559 AAH17559 BI560657 BI828497 EU446932 ABZ92461 R42082 NM_001253676 NP_001240605 NM_004865 NP_004856 |
Function | Part of a specialized transcription system that mediates the transcription of most ribosomal proteins through the 5'-TCT-3' motif which is a core promoter element at these genes. Seems to also mediate the transcription of NF1. Does not bind the TATA box. {ECO:0000269|PubMed:10082669, ECO:0000269|PubMed:10220372, ECO:0000269|PubMed:15767669, ECO:0000269|PubMed:24958592}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. |
Tissue Specificity | Ubiquitously expressed, with highest levels in the testis and ovary. {ECO:0000269|PubMed:10082669, ECO:0000269|PubMed:17570761}. |
Top Pathways | Huntington's disease, HTLV-I infection, Herpes simplex infection, Viral carcinogenesis, Epstein-Barr virus infection |
Human TBP like protein TLP full length protein - ab131906 from Abcam
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Human TBP like protein TLP full length protein - ab139211 from Abcam
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Human TBP like protein TLP peptide - ab22951 from Abcam
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TBPL1 / TRF2 Antibody Blocking Peptide - LS-E25422 from LifeSpan Bioscience
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TBPL1 / TRF2 Antibody Blocking Peptide - LS-E12706 from LifeSpan Bioscience
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TBP like protein TLP Partial Recombinant Protein - H00009519-Q01 from Novus Biologicals
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Recombinant Human TBP like protein TLP Protein - H00009519-P01 from Novus Biologicals
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TBP like protein TLP Protein - NBP2-22853 from Novus Biologicals
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TBPL1-Antibody-Center-Blocking-Peptide - BP19449c from Abgent, a WuXi AppTec company
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TLP blocking peptide - GTX89890-PEP from GeneTex
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Human TBPL1 protein - orb246235 from Biorbyt
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Goat anti TBPL1 antibody Immunizing peptide - orb17709 from Biorbyt
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TBPL1 protein (His tag) - 30R-2960 from Fitzgerald
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TBP like Protein TLP Peptide - AC21-0250-P from Abcore
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TBPL1 (1-186, His-tag) - AR50720PU-N from Acris Antibodies
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TBPL1 (1-186, His-tag) - AR50720PU-S from Acris Antibodies
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TBPL1 - H00009519-P01-02 from Acris Antibodies
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TBPL1 - H00009519-Q01-10 from Acris Antibodies
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TBPL1 - H00009519-Q01-25 from Acris Antibodies
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TBPL1, 1-186aa, Human, His tag, E.coli - 01-P1896 from ARP American Research Products
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TRF2 Peptide - 46-514P from ProSci
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TBPL1 fusion protein - Ag2880 from Proteintech Group
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Human TBPL1 Recombinant Protein - GWB-PPAT58 from Genway Biotech
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Recombinant Human TBPL1, His-tagged - TBPL1-7114H from Creative Biomart
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Recombinant Human TBPL1, GST-tagged - TBPL1-3136H from Creative Biomart
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