TREM2

Gene Symbol TREM2
Entrez Gene 54209
Alt Symbol TREM-2, Trem2a, Trem2b, Trem2c
Species Human
Gene Type protein-coding
Description triggering receptor expressed on myeloid cells 2
Other Description triggering receptor expressed on monocytes 2|triggering receptor expressed on myeloid cells 2a
Swissprots Q8WYN6 Q9NZC2 Q8N5H8
Accessions ABB01002 BAJ34724 EAX04032 EAX04033 EAX04034 Q9NZC2 AB062787 BAB78736 AF213457 AAF69824 AK312215 BAG35148 BC018284 BC032362 AAH32362 DQ891310 ABM82236 DQ894494 ABM85420 XM_006715116 XP_006715179 NM_001271821 NP_001258750 NM_018965 NP_061838
Function May have a role in chronic inflammations and may stimulate production of constitutive rather than inflammatory chemokines and cytokines. Forms a receptor signaling complex with TYROBP and triggers activation of the immune responses in macrophages and dendritic cells. {ECO:0000269|PubMed:10799849}.
Subcellular Location Isoform 3: Secreted {ECO:0000305}.
Tissue Specificity Expressed on macrophages and dendritic cells but not on granulocytes or monocytes. In the CNS strongest expression seen in the basal ganglia, corpus callosum, medulla oblongata and spinal cord. {ECO:0000269|PubMed:10799849, ECO:0000269|PubMed:12080485}.
Top Pathways Osteoclast differentiation

TREM-2 CRISPR/Cas9 KO Plasmid (h) - sc-401585 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TREM-2 HDR Plasmid (h) - sc-401585-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TREM-2 Double Nickase Plasmid (h) - sc-401585-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TREM-2 Double Nickase Plasmid (h2) - sc-401585-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TREM-2 CRISPR Activation Plasmid (h) - sc-401585-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TREM-2 CRISPR Activation Plasmid (h2) - sc-401585-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TREM-2 Lentiviral Activation Particles (h) - sc-401585-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TREM-2 Lentiviral Activation Particles (h2) - sc-401585-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TREM-2 siRNA (h) - sc-43001 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TREM-2 shRNA Plasmid (h) - sc-43001-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TREM-2 shRNA (h) Lentiviral Particles - sc-43001-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TREM-2 RNAi - H00054209-R02 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU079401 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN21938 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21938 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR01373 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr01373

TREM2 siRNA (Human) - CRJ0032 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TREM2 - MBS8217328 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human TREM2 (NM_018965.2) - SHH434156 from Creative biogene

Category siRNA
Species Reactivities Human

TREM2 shRNA Plasmid (Human) - CHJ0032 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

TREM2 miRNA 3'UTR clone - MiUTR3H-07361 from Creative biogene

Species Reactivities Human
Search more