TREM2

Gene Symbol	TREM2
Entrez Gene	54209
Alt Symbol	TREM-2, Trem2a, Trem2b, Trem2c
Species	Human
Gene Type	protein-coding
Description	triggering receptor expressed on myeloid cells 2
Other Description	triggering receptor expressed on monocytes 2|triggering receptor expressed on myeloid cells 2a
Swissprots	Q8WYN6 Q9NZC2 Q8N5H8
Accessions	ABB01002 BAJ34724 EAX04032 EAX04033 EAX04034 Q9NZC2 AB062787 BAB78736 AF213457 AAF69824 AK312215 BAG35148 BC018284 BC032362 AAH32362 DQ891310 ABM82236 DQ894494 ABM85420 XM_006715116 XP_006715179 NM_001271821 NP_001258750 NM_018965 NP_061838
Function	May have a role in chronic inflammations and may stimulate production of constitutive rather than inflammatory chemokines and cytokines. Forms a receptor signaling complex with TYROBP and triggers activation of the immune responses in macrophages and dendritic cells. {ECO:0000269|PubMed:10799849}.
Subcellular Location	Isoform 3: Secreted {ECO:0000305}.
Tissue Specificity	Expressed on macrophages and dendritic cells but not on granulocytes or monocytes. In the CNS strongest expression seen in the basal ganglia, corpus callosum, medulla oblongata and spinal cord. {ECO:0000269|PubMed:10799849, ECO:0000269|PubMed:12080485}.
Top Pathways	Osteoclast differentiation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human TREM-2 (NP_061838) VersaClone cDNA - RDC0861 from R&D Systems Prices $199.00 Sizes 10 µg Species Human

Human TREM2 ORF clone(NM_018965.2) - CDCG004102 from Creative Biomart Species Human Accession NM_018965.2

Human TREM2 ORF Clone(NM_018965.2) - CDCL179550 from Creative Biomart Species Human Accession NM_018965.2

Human TREM2 ORF Clone(NM_018965.2) - CDCL179551 from Creative Biomart Species Human Accession NM_018965.2

human TREM2 ORF clone - CDCH094712 from Creative Biomart Species Human Accession NM_018965

human TREM2 ORF clone - CDCH094713 from Creative Biomart Species Human Accession NM_018965

human TREM2 ORF clone - CDCH094714 from Creative Biomart Species Human Accession NM_018965

human TREM2 ORF clone - CDCH094715 from Creative Biomart Species Human Accession NM_018965

human TREM2 ORF clone - CDCH094716 from Creative Biomart Species Human Accession NM_018965

human TREM2 ORF clone - CDCH094717 from Creative Biomart Species Human Accession NM_018965

Human TREM2 Gene cDNA clone plasmid - HG11084-M from Sino Biological Species Human

Human TREM2 ORF clone(NM_018965.2) - CDCG004102 from Creative biogene Species Human

Human TREM-2/TREM2 Gene ORF cDNA clone expression plasmid, N-HA tag - HG11084-NY from Sino Biological Species Human

Human TREM-2/TREM2 Gene ORF cDNA clone expression plasmid, C-HA tag - HG11084-CY from Sino Biological Species Human

Human TREM-2/TREM2 Gene ORF cDNA clone expression plasmid, C-His tag - HG11084-CH from Sino Biological Species Human

Human TREM-2/TREM2 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG11084-ACG from Sino Biological Species Human

Human TREM-2/TREM2 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG11084-CF from Sino Biological Species Human

Human TREM-2/TREM2 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG11084-NM from Sino Biological Species Human

Human TREM-2/TREM2 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG11084-ACR from Sino Biological Species Human

Human TREM-2/TREM2 Gene ORF cDNA clone expression plasmid, N-His tag - HG11084-NH from Sino Biological Species Human

Human TREM-2/TREM2 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG11084-CM from Sino Biological Species Human

Human TREM-2/TREM2 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG11084-NF from Sino Biological Species Human

Human TREM-2/TREM2 Gene ORF cDNA clone expression plasmid - HG11084-UT from Sino Biological Species Human

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