TREM2

Gene Symbol	TREM2
Entrez Gene	54209
Alt Symbol	TREM-2, Trem2a, Trem2b, Trem2c
Species	Human
Gene Type	protein-coding
Description	triggering receptor expressed on myeloid cells 2
Other Description	triggering receptor expressed on monocytes 2|triggering receptor expressed on myeloid cells 2a
Swissprots	Q8WYN6 Q9NZC2 Q8N5H8
Accessions	ABB01002 BAJ34724 EAX04032 EAX04033 EAX04034 Q9NZC2 AB062787 BAB78736 AF213457 AAF69824 AK312215 BAG35148 BC018284 BC032362 AAH32362 DQ891310 ABM82236 DQ894494 ABM85420 XM_006715116 XP_006715179 NM_001271821 NP_001258750 NM_018965 NP_061838
Function	May have a role in chronic inflammations and may stimulate production of constitutive rather than inflammatory chemokines and cytokines. Forms a receptor signaling complex with TYROBP and triggers activation of the immune responses in macrophages and dendritic cells. {ECO:0000269|PubMed:10799849}.
Subcellular Location	Isoform 3: Secreted {ECO:0000305}.
Tissue Specificity	Expressed on macrophages and dendritic cells but not on granulocytes or monocytes. In the CNS strongest expression seen in the basal ganglia, corpus callosum, medulla oblongata and spinal cord. {ECO:0000269|PubMed:10799849, ECO:0000269|PubMed:12080485}.
Top Pathways	Osteoclast differentiation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human TREM2 / TREM-2 ELISA Kit (Sandwich ELISA) - LS-F6690 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 95 pg/ml Range 62.5-4000 pg/ml

Mouse TREM2 / TREM-2 ELISA Kit (Sandwich ELISA) - LS-F7884 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 15.63 pg/ml Range 62.5-4000 pg/ml

Human TREM2 / TREM-2 ELISA Kit (Sandwich ELISA) - LS-F12847 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 78 Range 62.5-4000 pg/ml

Mouse TREM2 / TREM-2 ELISA Kit (Sandwich ELISA) - LS-F12848 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 78 pg/ml Range 62.5-4000 pg/ml

Triggering receptor expressed on myeloid cells 2 (TREM2), Human, ELISA Kit - CSB-EL024405HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Triggering Receptor Expressed On Myeloid Cells 2 (TREM2), Human, ELISA Kit - SEG628Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 21.9pg/mL Range 62.5-4,000pg/mL

Triggering receptor expressed on myeloid cells 2, TREM2, Human, ELISA Kit - E12753h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 78-5000 pg/mL

Custom Human TREM-2 ELISA - ELH-TREM2 from RayBiotech Category ELISA Kit Prices $615.00, $1,107.00, $2,460.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit

triggering receptor expressed on myeloid cells 2, ELISA Kit - MBS928570 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.078 ng/ml. Range 0.312 ng/ml-20 ng/ml.

Triggering Receptor Expressed On Myeloid Cells 2 (TREM2), ELISA Kit - MBS9309044 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Triggering Receptor Expressed On Myeloid Cells 2 (TREM2), ELISA Kit - MBS2023874 from MyBioSource Category ELISA Kit Prices $385.00, $575.00, $785.00, $3,210.00, $5,825.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 6.2pg/mL. Range 15.6-1,000pg/mL. The standard curve concentrations used for the ELISA's were 1,000pg/mL, 500pg/mL, 250pg/mL, 125pg/mL, 62.5pg/mL, 31.2pg/mL, 15.6pg/mL.

Triggering Receptor Expressed On Myeloid Cells 2 (TREM2), ELISA Kit - MBS2022102 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 25.5pg/mL. Range 62.5-4000pg/mL

Human TREM-2 / TREM2 ELISA Pair Set - SEK11084-5 from Sino Biological Category ELISA Kit Prices $350.00, $350.00 Sizes 5 plates, 15 plates

ELISA Kit for Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) - SEG628Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 25.5pg/mL. Range 62.5-4000pg/mL The standard curve concentrations used for the ELISA’s were 4000pg/mL, 2000pg/mL, 1000pg/mL, 500pg/mL, 250pg/mL, 125pg/mL, 62.5pg/mL

ELISA Kit for Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) - SEG628Mu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 6.4pg/mL. Range 15.63-1000pg/mL The standard curve concentrations used for the ELISA’s were 1000pg/mL, 500pg/mL, 250pg/mL, 125pg/mL, 62.5pg/mL, 31.25pg/mL, 15.63pg/mL

Human Triggering receptor expressed on myeloid cells 2(TREM2) ELISA kit - CSB-EL024405HU from Cusabio Category ELISA Kit Sensitivity 0.078 ng/ml Range 0.312 ng/ml-20 ng/ml

ELISA Kit for Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) - SEG628Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 25.5pg/mL. Range 62.5-4000pg/mL The standard curve concentrations used for the ELISA's were 4000pg/mL, 2000pg/mL, 1000pg/mL, 500pg/mL, 250pg/mL, 125pg/mL, 62.5pg/mL

Human Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) ELISA Kit - EKU07882 from Biomatik Category ELISA Kit Prices $735.00, $3,234.00, $5,880.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 26.2 pg/mL Range 62.5-4000 pg/mL

Human TREM2 ELISA Kit - abx153387 from Abbexa Category ELISA Kit Sensitivity 23.9 pg/ml Range 62.5 pg/ml - 4000 pg/ml

Human Triggering receptor expressed on myeloid cells 2 ELISA Kit - abx250733 from Abbexa Category ELISA Kit Range 78 pg/ml - 5000 pg/ml

Triggering Receptor Expressed On Myeloid Cells 2 (TREM2), Human, ELISA Kit - DL-TREM2-Hu from ARP American Research Products Category ELISA Kit Prices $655.00 Sizes 96 t Range 62.5-4,000 pg/mL

Human TREM-2 ELISA Kit - DEIA-XY2250 from Creative Diagnostics Category ELISA Kit Sensitivity 20 pg/mL Range 62.5-4000 pg/ml

Human TREM-2 ELISA Pair Set - orb146011 from Biorbyt Category ELISA Kit Prices $510.00, $1,148.00 Sizes 5 plates, 15 plates

Human TREM2 ELISA Kit - abx576048 from Abbexa Category ELISA Kit Sensitivity 21.9 pg/ml Range 62.5 pg/ml - 4000 pg/ml

Human TREM-2 ELISA Kit - RAB1091 from Sigma-Aldrich Category ELISA Kit Prices $448.00 Sizes 1 kt Sensitivity 28 pg/ml

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