AP1AR

Gene Symbol AP1AR
Entrez Gene 55435
Alt Symbol 2C18, C4orf16, GBAR, PRO0971, gamma-BAR
Species Human
Gene Type protein-coding
Description adaptor-related protein complex 1 associated regulatory protein
Other Description AP-1 complex-associated regulatory protein|adapter-related protein complex 1-associated regulatory protein|adaptor-related protein complex 1-associated regulatory protein|gadkin|gamma-1-adaptin brefeldin A resistance protein|gamma-A1-adaptin and kinesin interactor|gamma1-adaptin brefeldin A resistance protein, gamma-BAR
Swissprots Q9P1L4 Q96GG6 Q63HQ0 Q9H0V0 B2RCV7
Accessions AAY40962 EAX06268 EAX06269 EAX06270 EAX06271 EAX06272 Q63HQ0 AF116612 AAF71037 AI273122 AK310787 AK315299 BAG37704 AL136628 CAB66563 AM392774 CAL37652 AM393046 CAL37924 AM393154 CAL38032 AM393604 CAL38480 AM393708 CAL38584 BC009485 AAH09485 BM974015 BX647702 CAH56145 DA463845 EU831660 ACE87260 EU831743 ACE86577 XM_005263116 XP_005263173 XM_011532100 XP_011530402 NM_001128426 NP_001121898 NM_018569 NP_061039
Function Necessary for adaptor protein complex 1 (AP-1)-dependent transport between the trans-Golgi network and endosomes. Regulates the membrane association of AP1G1/gamma1-adaptin, one of the subunits of the AP-1 adaptor complex. The direct interaction with AP1G1/gamma1-adaptin attenuates the release of the AP-1 complex from membranes. Regulates endosomal membrane traffic via association with AP-1 and KIF5B thus linking kinesin-based plus- end-directed microtubular transport to AP-1-dependent membrane traffic. May act as effector of AP-1 in calcium-induced endo- lysosome secretion. Inhibits Arp2/3 complex function; negatively regulates cell spreading, size and motility via intracellular sequestration of the Arp2/3 complex. {ECO:0000269|PubMed:15775984, ECO:0000269|PubMed:19706427, ECO:0000269|PubMed:21525240, ECO:0000269|PubMed:22689987}.
Subcellular Location Golgi apparatus, trans-Golgi network. Late endosome. Early endosome. Note=Localizes to the juxta-nuclear Golgi region and to tubular structures throughout the cytoplasm, which are highly mobile and cycle between the juxta-nuclear area and the cell periphery.

AP1AR (C-6) - sc-398565 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
AP1AR (C-6): sc-398565. Western blot analysis of AP1AR expression in HeLa (A), AN3 CA (B), Jurkat (C) and Ca Ski (D) whole cell lysates and human cervix tissue extract (E).

AP1AR (S-15) - sc-163909 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-AP1AR antibody - ab122296 from Abcam

Prices $443.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab122296, at a 1/200 dilution, staining AP1AR in paraffin embedded Human oral mucosa by Immunohistochemistry.

Anti-AP1AR antibody - C-terminal - ab157638 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-AP1AR antibody - C-terminal (ab157638) at 1 µg/ml + Jurkat whole cell lysate at 10 µg

Anti-AP1AR Antibody (aa202-251) - LS-C170549 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

AP1AR Antibody - NBP1-90879 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: AP1AR Antibody [NBP1-90879] - Staining of human placenta shows cytoplasmic positivity in trophoblasts.

Anti-AP1AR (66-80) antibody produced in rabbit - SAB1104631 from Sigma-Aldrich

Prices $285.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-AP1AR antibody produced in rabbit - HPA035863 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-AP1AR: <B>Cat. No. HPA035863</B>: Immunohistochemical staining of human oral mucosa shows strong cytoplasmic and nucleolar/ or nuclear positivity in squamous epithelial cells.

Anti-AP1AR (266-280) antibody produced in rabbit - SAB1104632 from Sigma-Aldrich

Prices $285.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

AP1AR Antibody - C-terminal region (ARP68722_P050) - ARP68722_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

C4orf16 antibody - H00055435-B01P from Acris Antibodies

Prices $1,530.00
Sizes 500 µg
Host Mouse
Clonality Polyclonal

Anti-AP1AR (aa 202-251) polyclonal antibody - DPABH-05956 from Creative Diagnostics

Host Rabbit
Clonality Polyclonal

Anti-AP1AR (aa 2-82) polyclonal antibody - DPABH-20591 from Creative Diagnostics

Host Rabbit
Clonality Polyclonal

AP1AR antibody - TA330683 from Acris Antibodies

Prices $325.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Host: Rabbit; Target Name: AP1AR; Sample Tissue: Jurkat Whole Cell lysates; Antibody Dilution: 1.0ug/ml

AP1AR antibody - orb326787 from Biorbyt

Prices $502.00
Sizes 100 μl
Host Rabbit
Clonality Polyclonal

Anti-AP1AR Antibody A10498 - A10498 from Boster Bio

Prices $299.00
Sizes 1
Host Rabbit
Clonality Polyclonal

AP1AR Antibody - NBP2-58664 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: AP1AR Antibody [NBP2-58664] - Staining of human cell line U-2 OS shows localization to the Golgi apparatus.

AP1AR Antibody - C-terminal region : Biotin (ARP68722_P050-Biotin) - ARP68722_P050-Biotin from Aviva Systems Biology

Host Rabbit
Clonality Polyclonal

AP1AR Antibody - C-terminal region : FITC (ARP68722_P050-FITC) - ARP68722_P050-FITC from Aviva Systems Biology

Host Rabbit
Clonality Polyclonal

AP1AR Antibody - C-terminal region : HRP (ARP68722_P050-HRP) - ARP68722_P050-HRP from Aviva Systems Biology

Host Rabbit
Clonality Polyclonal

AP1AR antibody - N-terminal region (OAAB06313) - OAAB06313 from Aviva Systems Biology

Host Rabbit
Clonality Polyclonal

Anti-AP1AR Antibody (aa202-251, HRP) - LS-C476076 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-AP1AR Antibody (aa202-251, Biotin) - LS-C476074 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-AP1AR Antibody (aa202-251, FITC) - LS-C476075 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
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