AP1AR

Gene Symbol	AP1AR
Entrez Gene	55435
Alt Symbol	2C18, C4orf16, GBAR, PRO0971, gamma-BAR
Species	Human
Gene Type	protein-coding
Description	adaptor-related protein complex 1 associated regulatory protein
Other Description	AP-1 complex-associated regulatory protein|adapter-related protein complex 1-associated regulatory protein|adaptor-related protein complex 1-associated regulatory protein|gadkin|gamma-1-adaptin brefeldin A resistance protein|gamma-A1-adaptin and kinesin interactor|gamma1-adaptin brefeldin A resistance protein, gamma-BAR
Swissprots	Q9P1L4 Q96GG6 Q63HQ0 Q9H0V0 B2RCV7
Accessions	AAY40962 EAX06268 EAX06269 EAX06270 EAX06271 EAX06272 Q63HQ0 AF116612 AAF71037 AI273122 AK310787 AK315299 BAG37704 AL136628 CAB66563 AM392774 CAL37652 AM393046 CAL37924 AM393154 CAL38032 AM393604 CAL38480 AM393708 CAL38584 BC009485 AAH09485 BM974015 BX647702 CAH56145 DA463845 EU831660 ACE87260 EU831743 ACE86577 XM_005263116 XP_005263173 XM_011532100 XP_011530402 NM_001128426 NP_001121898 NM_018569 NP_061039
Function	Necessary for adaptor protein complex 1 (AP-1)-dependent transport between the trans-Golgi network and endosomes. Regulates the membrane association of AP1G1/gamma1-adaptin, one of the subunits of the AP-1 adaptor complex. The direct interaction with AP1G1/gamma1-adaptin attenuates the release of the AP-1 complex from membranes. Regulates endosomal membrane traffic via association with AP-1 and KIF5B thus linking kinesin-based plus- end-directed microtubular transport to AP-1-dependent membrane traffic. May act as effector of AP-1 in calcium-induced endo- lysosome secretion. Inhibits Arp2/3 complex function; negatively regulates cell spreading, size and motility via intracellular sequestration of the Arp2/3 complex. {ECO:0000269|PubMed:15775984, ECO:0000269|PubMed:19706427, ECO:0000269|PubMed:21525240, ECO:0000269|PubMed:22689987}.
Subcellular Location	Golgi apparatus, trans-Golgi network. Late endosome. Early endosome. Note=Localizes to the juxta-nuclear Golgi region and to tubular structures throughout the cytoplasm, which are highly mobile and cycle between the juxta-nuclear area and the cell periphery.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human AP1AR full length protein - ab171698 from Abcam Category Protein Prices $297.00 Sizes 20 µg Source E. coli Species Human

AP1AR Antibody Blocking Peptide - LS-E24649 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human AP1AR Protein - NBP2-22677 from Novus Biologicals Category Protein Prices $269.00 Sizes 20 µg Source E.coli Species Human

C4orf16-Antibody-N-term-Blocking-Peptide - BP9714a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

AP1AR protein (His tag) - 80R-3027 from Fitzgerald Category Protein Prices $275.00 Sizes 20 µg Source E.coli

AP1AR (1-302, His-tag) - AR51145PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 100 µg Source E. coli Species Human

AP1AR (1-302, His-tag) - AR51145PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 20 µg Source E. coli Species Human

AP1AR, 1-302aa, Human, His tag, E.coli - 01-P2321 from ARP American Research Products Category Protein Prices $139.00, $369.00, $849.00 Sizes 5 µg, 20 µg, 100 µg Species Human

AP1AR, 1-302aa, Human, His tag, E.coli - GWB-ATG504 from Genway Biotech Category Protein Prices $300.00, $900.00 Sizes 20 μg, 100 μg Species Human

Recombinant Human AP1AR, His-tagged - AP1AR-2321H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human AP-1 complex-associated regulatory protein(AP1AR) - CSB-YP737264HU CSB-EP737264HU CSB-BP737264HU CSB-MP737264HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

AP1AR, 1-302aa, Human, His tag, E.coli - ATGP2321 from ATGen Category Protein Prices $80.00, $240.00, $720.00 Sizes 4 µg, 20 µg, 100 µg Species Human

Adducin-related protein 1(add-1) ,partial - MBS145704 from MyBioSource Category Protein Prices $140.00, $205.00, $1,220.00 Sizes 2 µg, 10 µg, 100 µg Source E Coli

AP-1 complex-associated regulatory protein (AP1AR) , Recombinant Protein - MBS1487189 from MyBioSource Category Protein Prices $1,655.00, $1,655.00, $2,115.00, $2,115.00 Sizes 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

AP1AR, Recombinant Protein - MBS204802 from MyBioSource Category Protein Prices $310.00, $720.00 Sizes 20 µg, 100 µg Source E Coli Species Human

Human AP1AR protein - orb259794 from Biorbyt Category Protein Prices $170.00, $289.00, $1,122.00 Sizes 2 μg, 10 μg, 100 μg Species Human

AP1AR Recombinant Protein Antigen - NBP1-90879PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

AP1AR Peptide, Human - M34GP00710H from Creative Peptides Category Peptide Source Synthetic. Species Human

AP1AR - PAT-82320-1 from Nordic BioSite Category Protein Species Human

AP1AR - PAT-82320-2 from Nordic BioSite Category Protein Species Human

AP1AR Recombinant Protein Antigen - NBP2-58664PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

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