AP1AR

Gene Symbol AP1AR
Entrez Gene 55435
Alt Symbol 2C18, C4orf16, GBAR, PRO0971, gamma-BAR
Species Human
Gene Type protein-coding
Description adaptor-related protein complex 1 associated regulatory protein
Other Description AP-1 complex-associated regulatory protein|adapter-related protein complex 1-associated regulatory protein|adaptor-related protein complex 1-associated regulatory protein|gadkin|gamma-1-adaptin brefeldin A resistance protein|gamma-A1-adaptin and kinesin interactor|gamma1-adaptin brefeldin A resistance protein, gamma-BAR
Swissprots Q9P1L4 Q96GG6 Q63HQ0 Q9H0V0 B2RCV7
Accessions AAY40962 EAX06268 EAX06269 EAX06270 EAX06271 EAX06272 Q63HQ0 AF116612 AAF71037 AI273122 AK310787 AK315299 BAG37704 AL136628 CAB66563 AM392774 CAL37652 AM393046 CAL37924 AM393154 CAL38032 AM393604 CAL38480 AM393708 CAL38584 BC009485 AAH09485 BM974015 BX647702 CAH56145 DA463845 EU831660 ACE87260 EU831743 ACE86577 XM_005263116 XP_005263173 XM_011532100 XP_011530402 NM_001128426 NP_001121898 NM_018569 NP_061039
Function Necessary for adaptor protein complex 1 (AP-1)-dependent transport between the trans-Golgi network and endosomes. Regulates the membrane association of AP1G1/gamma1-adaptin, one of the subunits of the AP-1 adaptor complex. The direct interaction with AP1G1/gamma1-adaptin attenuates the release of the AP-1 complex from membranes. Regulates endosomal membrane traffic via association with AP-1 and KIF5B thus linking kinesin-based plus- end-directed microtubular transport to AP-1-dependent membrane traffic. May act as effector of AP-1 in calcium-induced endo- lysosome secretion. Inhibits Arp2/3 complex function; negatively regulates cell spreading, size and motility via intracellular sequestration of the Arp2/3 complex. {ECO:0000269|PubMed:15775984, ECO:0000269|PubMed:19706427, ECO:0000269|PubMed:21525240, ECO:0000269|PubMed:22689987}.
Subcellular Location Golgi apparatus, trans-Golgi network. Late endosome. Early endosome. Note=Localizes to the juxta-nuclear Golgi region and to tubular structures throughout the cytoplasm, which are highly mobile and cycle between the juxta-nuclear area and the cell periphery.

C4orf16-Over-expression-Lysate - LY16258a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag C4orf16 (arrow) using his tag antibody. 293T cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the C4orf16 gene‘

AP1AR 293 Cell Lysate - 406308 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

AP1AR Overexpression Lysate (Native) - NBP2-06788 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: AP1AR Overexpression Lysate (Adult Normal) [NBP2-06788] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for AP1AR.

AP1AR Over-expression Lysate Product - GWB-A87008 from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

Panoply™ Human AP1AR Knockdown Stable Cell Line - CSC-DC000710 from Creative biogene

Category Cell Line
Species Human
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