MOCS2

Gene Symbol MOCS2
Entrez Gene 4338
Alt Symbol MCBPE, MOCO1, MOCODB, MPTS
Species Human
Gene Type protein-coding
Description molybdenum cofactor synthesis 2
Other Description MOCS2A|MOCS2B|molybdenum cofactor biosynthesis protein E|molybdopterin synthase small and large subunit|molybdopterin synthase sulfur carrier subunit
Swissprots O96007 O96033 Q6IAI3
Accessions CBG03804 CBV17326 EAW54874 EAW54875 EAW54876 EAW54877 O96007 O96033 AA252410 AF091871 AAD14598 AF117815 AAD13296 AF155659 AAF67478 AK095832 AK126211 AK312887 BAG35735 BC029287 BC039720 BC046097 AAH46097 BC095417 CB050849 CD514049 CR457172 CAG33453 DA967651 NM_004531 NP_004522 NM_176806 NP_789776
Function Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group. {ECO:0000255|HAMAP-Rule:MF_03052, ECO:0000269|PubMed:12732628, ECO:0000269|PubMed:15073332}.
Subcellular Location Cytoplasm, cytosol {ECO:0000255|HAMAP- Rule:MF_03052, ECO:0000269|PubMed:15073332}.
Tissue Specificity Highest levels are found in heart and skeletal muscle. Lower levels are present in brain, kidney and pancreas. Very low levels are found in lung and peripheral blood leukocytes. {ECO:0000269|PubMed:10053003}.
Top Pathways Sulfur relay system, Folate biosynthesis

MOCS2 CRISPR/Cas9 KO Plasmid (h) - sc-407720 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MOCS2 HDR Plasmid (h) - sc-407720-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MOCS2 Double Nickase Plasmid (h) - sc-407720-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MOCS2 Double Nickase Plasmid (h2) - sc-407720-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MOCS2 CRISPR Activation Plasmid (h) - sc-407720-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MOCS2 CRISPR Activation Plasmid (h2) - sc-407720-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MOCS2 Lentiviral Activation Particles (h) - sc-407720-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MOCS2 Lentiviral Activation Particles (h2) - sc-407720-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MOCS2 siRNA (h) - sc-72268 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MOCS2 shRNA Plasmid (h) - sc-72268-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MOCS2 shRNA (h) Lentiviral Particles - sc-72268-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU079461 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN14460 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14460 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR05921 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr05921

MOCS2 siRNA (Human) - CRH2947 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

MOCS2 siRNA (Human) - CRH2948 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human MOCS2 (NM_176806.2) - SHH343380 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human MOCS2(NM_004531.3) - SHH195149 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human MOCS2(NM_176806.2) - SHH195203 from Creative biogene

Category siRNA
Species Reactivities Human

Human MOCS2 siRNA - orb263450 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Human MOCS2 siRNA - orb263449 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

MOCS2 shRNA Plasmid (Human) - CHH2947 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

MOCS2 shRNA Plasmid (Human) - CHH2948 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

MOCS2 miRNA 3'UTR clone - MiUTR1H-06375 from Creative biogene

Species Reactivities Human
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