Gene Symbol | MOCS2 |
---|---|
Entrez Gene | 4338 |
Alt Symbol | MCBPE, MOCO1, MOCODB, MPTS |
Species | Human |
Gene Type | protein-coding |
Description | molybdenum cofactor synthesis 2 |
Other Description | MOCS2A|MOCS2B|molybdenum cofactor biosynthesis protein E|molybdopterin synthase small and large subunit|molybdopterin synthase sulfur carrier subunit |
Swissprots | O96007 O96033 Q6IAI3 |
Accessions | CBG03804 CBV17326 EAW54874 EAW54875 EAW54876 EAW54877 O96007 O96033 AA252410 AF091871 AAD14598 AF117815 AAD13296 AF155659 AAF67478 AK095832 AK126211 AK312887 BAG35735 BC029287 BC039720 BC046097 AAH46097 BC095417 CB050849 CD514049 CR457172 CAG33453 DA967651 NM_004531 NP_004522 NM_176806 NP_789776 |
Function | Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group. {ECO:0000255|HAMAP-Rule:MF_03052, ECO:0000269|PubMed:12732628, ECO:0000269|PubMed:15073332}. |
Subcellular Location | Cytoplasm, cytosol {ECO:0000255|HAMAP- Rule:MF_03052, ECO:0000269|PubMed:15073332}. |
Tissue Specificity | Highest levels are found in heart and skeletal muscle. Lower levels are present in brain, kidney and pancreas. Very low levels are found in lung and peripheral blood leukocytes. {ECO:0000269|PubMed:10053003}. |
Top Pathways | Sulfur relay system, Folate biosynthesis |
Human MOCS2 full length protein - ab134527 from Abcam
|
||||||||||
MOCS2 Antibody Blocking Peptide - LS-E4054 from LifeSpan Bioscience
|
||||||||||
MOCS2 Recombinant Protein - H00004338-P01 from Novus Biologicals
|
||||||||||
Recombinant Human MOCS2 Protein - NBP2-23250 from Novus Biologicals
|
||||||||||
MOCS2-Antibody-N-term-Blocking-Peptide - BP16279a from Abgent, a WuXi AppTec company
|
||||||||||
Human MOCS2 protein - orb168849 from Biorbyt
|
||||||||||
MOCS2 protein (His tag) - 80R-2464 from Fitzgerald
|
||||||||||
MOCS2 (1-188, His-tag) - AR50536PU-N from Acris Antibodies
|
||||||||||
MOCS2 (1-188, His-tag) - AR50536PU-S from Acris Antibodies
|
||||||||||
MOCS2 - H00004338-P01-10 from Acris Antibodies
|
||||||||||
MOCS2 - H00004338-P01-25 from Acris Antibodies
|
||||||||||
MOCS2, 1-188aa, Human, His tag, E.coli - 01-P1712 from ARP American Research Products
|
||||||||||
MOCS2 fusion protein - Ag6282 from Proteintech Group
|
||||||||||
MOCS2 fusion protein - Ag5761 from Proteintech Group
|
||||||||||
MOCS2 Human - PRPS-1288 from NeoScientific
|
||||||||||
Recombinant Human MOCS2 Protein - BP001329-C839 from Syd Labs
|
||||||||||
Recombinant Human MOCS2 Protein - BP001329-PRO-1281 from Syd Labs
|
||||||||||
MOCS2, 1-188aa, Recombinant Protein - GWB-P0326A from Genway Biotech
|
||||||||||
Recombinant Human Molybdenum Cofactor Synthesis 2, His-tagged - MOCS2-7145H from Creative Biomart
|
||||||||||
Recombinant Human Molybdopterin synthase sulfur carrier subunit(MOCS2) - CSB-YP529746HU CSB-EP529746HU CSB-BP529746HU CSB-MP529746HU from Cusabio
|
||||||||||
Recombinant Molybdopterin synthase sulfur carrier subunit (CBG26118) - CSB-YP471826CXX CSB-EP471826CXX CSB-BP471826CXX CSB-MP471826CXX from Cusabio
|
||||||||||
Recombinant Human Molybdopterin synthase catalytic subunit(MOCS2) - CSB-YP014706HU CSB-EP014706HU CSB-BP014706HU CSB-MP014706HU from Cusabio
|
||||||||||
MOCS2, 1-188aa, Human, His tag, E.coli - ATGP1712 from ATGen
|
||||||||||
Molybdenum Cofactor Synthesis 2 Protein (Recombinant) - abx263321 from Abbexa
|
||||||||||
MOCS2 (transcript variant 1) - TP314804 from Acris Antibodies
|