MOCS2

Gene Symbol MOCS2
Entrez Gene 4338
Alt Symbol MCBPE, MOCO1, MOCODB, MPTS
Species Human
Gene Type protein-coding
Description molybdenum cofactor synthesis 2
Other Description MOCS2A|MOCS2B|molybdenum cofactor biosynthesis protein E|molybdopterin synthase small and large subunit|molybdopterin synthase sulfur carrier subunit
Swissprots O96007 O96033 Q6IAI3
Accessions CBG03804 CBV17326 EAW54874 EAW54875 EAW54876 EAW54877 O96007 O96033 AA252410 AF091871 AAD14598 AF117815 AAD13296 AF155659 AAF67478 AK095832 AK126211 AK312887 BAG35735 BC029287 BC039720 BC046097 AAH46097 BC095417 CB050849 CD514049 CR457172 CAG33453 DA967651 NM_004531 NP_004522 NM_176806 NP_789776
Function Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group. {ECO:0000255|HAMAP-Rule:MF_03052, ECO:0000269|PubMed:12732628, ECO:0000269|PubMed:15073332}.
Subcellular Location Cytoplasm, cytosol {ECO:0000255|HAMAP- Rule:MF_03052, ECO:0000269|PubMed:15073332}.
Tissue Specificity Highest levels are found in heart and skeletal muscle. Lower levels are present in brain, kidney and pancreas. Very low levels are found in lung and peripheral blood leukocytes. {ECO:0000269|PubMed:10053003}.
Top Pathways Sulfur relay system, Folate biosynthesis

MOCS2-Over-expression-Lysate - LY12934a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag MOCS2 (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the MOCS2 gene

MOCS2 overexpression lysate - LY406129 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

MOCS2 293 Cell Lysate - 408381 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

MOCS2 293 Cell Lysate - 403824 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

MOCS2 Overexpression Lysate (Native) - NBL1-13175 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg

MOCS2 (h): 293T Lysate - sc-116247 from Santa Cruz Biotechnology

Category Cell Lysate
Prices $205.00
Sizes 100 µg/200 µl
Species Human

MOCS2 Over-expression Lysate Product - GWB-F01AAA from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

MOCS2 Over-expression Lysate Product - GWB-E098BE from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

MOCS2 Overexpression Lysate (Native) - NBP2-05024 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: MOCS2 Overexpression Lysate (Adult Normal) [NBP2-05024] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for MOCS2.

Panoply™ Human MOCS2 Knockdown Stable Cell Line - CSC-DC009635 from Creative biogene

Category Cell Line
Species Human
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