Gene Symbol | ID4 |
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Entrez Gene | 3400 |
Alt Symbol | IDB4, bHLHb27 |
Species | Human |
Gene Type | protein-coding |
Description | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
Other Description | DNA-binding protein inhibitor ID-4|class B basic helix-loop-helix protein 27|inhibitor of differentiation 4 |
Swissprots | Q13005 P47928 |
Accessions | AAC39674 EAW55416 P47928 AI692586 AJ420553 AK130851 BC014941 AAH14941 DB461864 U16153 AAA82882 U28368 AAA73923 Y07958 CAA69255 NM_001546 NP_001537 |
Function | Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus. |
Top Pathways | TGF-beta signaling pathway, Signaling pathways regulating pluripotency of stem cells |
Human ID4 full length protein - ab114442 from Abcam
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Human ID4 protein fragment - ab112308 from Abcam
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ID4 Antibody Blocking Peptide - LS-E11306 from LifeSpan Bioscience
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ID4 Antibody Blocking Peptide - LS-E13650 from LifeSpan Bioscience
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ID4 Antibody Blocking Peptide - LS-E10431 from LifeSpan Bioscience
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Recombinant Human ID4 Protein - H00003400-Q01 from Novus Biologicals
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Recombinant Human ID4 Protein - H00003400-P01 from Novus Biologicals
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ID4-Antibody-N-term-Blocking-Peptide - BP9977a from Abgent, a WuXi AppTec company
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ID4 blocking peptide - GTX89728-PEP from GeneTex
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ID4 / BHLHB27 - H00003400-P01-10 from Acris Antibodies
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ID4 / BHLHB27 - H00003400-P01-25 from Acris Antibodies
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ID4 / BHLHB27 - H00003400-Q01-10 from Acris Antibodies
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ID4 / BHLHB27 - H00003400-Q01-25 from Acris Antibodies
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ID4 fusion protein - Ag17444 from Proteintech Group
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Recombinant Human ID4 - ID4-28078TH from Creative Biomart
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Recombinant Human ID4 - ID4-28592TH from Creative Biomart
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Recombinant Human ID4, His-tagged - ID4-14045H from Creative Biomart
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Id4 (S5) Peptide - BS2747P from Bioworld Technology
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Recombinant Human DNA-binding protein inhibitor ID-4(ID4) - CSB-YP010970HU CSB-EP010970HU CSB-BP010970HU CSB-MP010970HU from Cusabio
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ID4 fusion protein - Ag16883 from Proteintech Group
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ID4 / BHLHB27 - TP304170 from Acris Antibodies
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ID4 Protein - NBP2-37916PEP from Novus Biologicals
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ID4 Blocking Peptide - abx061218 from Abbexa
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ID4 Peptide, Human - M34GP07395H from Creative Peptides
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ID4 Blocking Peptide - CBP5131 from Cohesion Biosciences
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