| Gene Symbol |
ID4
|
| Entrez Gene |
3400
|
| Alt Symbol |
IDB4, bHLHb27
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
|
| Other Description |
DNA-binding protein inhibitor ID-4|class B basic helix-loop-helix protein 27|inhibitor of differentiation 4
|
| Swissprots |
Q13005 P47928
|
| Accessions |
AAC39674 EAW55416 P47928 AI692586 AJ420553 AK130851 BC014941 AAH14941 DB461864 U16153 AAA82882 U28368 AAA73923 Y07958 CAA69255 NM_001546 NP_001537
|
| Function |
Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Nucleus.
|
| Top Pathways |
TGF-beta signaling pathway, Signaling pathways regulating pluripotency of stem cells
|