COPG1

Gene Symbol COPG1
Entrez Gene 22820
Alt Symbol COPG
Species Human
Gene Type protein-coding
Description coatomer protein complex, subunit gamma 1
Other Description coat protein gamma-cop|coatomer subunit gamma|coatomer subunit gamma-1|gamma-1-COP|gamma-1-coat protein|gamma-COP|gamma-coat protein
Swissprots A8K6M8 B3KMF6 Q54AC4 Q9Y678
Accessions EAW79267 EAW79268 EAW79269 EAW79270 Q9Y678 AB047846 BAB17657 AF100756 AAD43020 AK001724 BAG50968 AK024721 AK025147 AK123939 BAG53983 AK291693 BAF84382 AK309821 BC020498 AAH20498 BC066650 AAH66650 BU521557 XM_011512549 XP_011510851 NM_016128 NP_057212
Function The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors. Required for limiting lipid storage in lipid droplets. Involved in lipid homeostasis by regulating the presence of perilipin family members PLIN2 and PLIN3 at the lipid droplet surface and promoting the association of adipocyte triglyceride lipase (PNPLA2) with the lipid droplet surface to mediate lipolysis (By
Subcellular Location Cytoplasm {ECO:0000269|PubMed:11056392}. Golgi apparatus membrane {ECO:0000269|PubMed:11056392}; Peripheral membrane protein {ECO:0000269|PubMed:11056392}; Cytoplasmic side {ECO:0000269|PubMed:11056392}. Cytoplasmic vesicle, COPI-coated vesicle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it. Predominantly located in the cis-Golgi apparatus. {ECO:0000250}.

COPG (H-4) - sc-271362 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
COPG (H-4): sc-271362. Western blot analysis of COPG expression in K-562 (A) and Ramos (B) whole cell lysates.

COPG (A-10) - sc-393977 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
COPG (A-10): sc-393977. Immunofluorescence staining of methanol-fixed HeLa cells showing Golgi apparatus and cytoplasmic localization.

COPG (H-300) - sc-30092 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
COPG (H-300): sc-30092. Western blot analysis of COPG expression in non-transfected 293T: sc-117752 (A), human COPG transfected 293T: sc-113185 (B) and K-562 (C) whole cell lysates.

COPG (K-16) - sc-23201 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

COPG (C-19) - sc-14167 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
COPG (C-19): sc-14167. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human breast tissue showing cytoplasmic staining.

Anti-COPG antibody - ab102044 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-COPG antibody (ab102044) at 1 µg/ml + THP1 cell lysate at 10 µg

Anti-COPG antibody - C-terminal - ab156132 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-COPG antibody - C-terminal (ab156132) at 1/100 dilution + A2058 cell line lysates at 35 µg

Anti-COPG / Gamma-COP Antibody (aa721-750, Biotin) - LS-C213391 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-COPG / Gamma-COP Antibody (aa721-750, PE) - LS-C213394 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-COPG / Gamma-COP Antibody (aa721-750) - LS-C157658 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
COPG Antibody western blot of A2058 cell line lysates (35 ug/lane). The COPG antibody detected the COPG protein (arrow).

Anti-COPG / Gamma-COP Antibody (aa721-750) - LS-C320521 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-COPG / Gamma-COP Antibody (N-Terminus) - LS-C116612 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
COPG antibody LS-C116612 Western blot of THP-1 cell lysate.

Anti-COPG / Gamma-COP Antibody (aa721-750, AP) - LS-C213389 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-COPG / Gamma-COP Antibody (aa721-750, APC) - LS-C213390 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-COPG / Gamma-COP Antibody (aa721-750, FITC) - LS-C213392 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-COPG / Gamma-COP Antibody (aa721-750, Azide-free, HRP) - LS-C213393 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

COPG Antibody - NBP1-85514 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: COPG Antibody [NBP1-85514] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp. Lane 4: Human plasma (IgG/HSA depleted). Lane 5: Human liver tissue. Lane 6: Human tonsil tissue

COPG Antibody - NBP1-57624 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: COPG Antibody [NBP1-57624] - THP-1 cell lysate, concentration 0.2-1 ug/ml.

COPG Antibody - NBP2-15959 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-COPG1 antibody produced in rabbit - HPA037867 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-COPG: <B>Cat. No. HPA037867</B>: Immunohistochemical staining of human colon shows strong cytoplasmic positivity with granular pattern in glandular cells.

Anti-COPG antibody produced in rabbit - SAB2700873 from Sigma-Aldrich

Prices $326.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-COPG (604-615) antibody produced in rabbit - SAB1101370 from Sigma-Aldrich

Prices $328.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-COPG (604-615) (RB): <B>Cat. No. SAB1101370</B>: Immunofluorescence of HUVEC cells using Anti-COPG (604-615) (RB) at a 1:50 dilution, taken at 40× magnification and nuclear staining with Hoescht 33342 (blue). Yale HTCB IF procedure used. Images may have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com

COPG antibody - N-terminal region (ARP55336_P050) - ARP55336_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

COPG-Antibody-C-term - AP19908b from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-COPG Antibody (C-term) at 1:1000 dilution Lane 1: A2058 whole cell lysate Lane 2: K562 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 98 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

COPG antibody [N3C2], Internal - GTX105331 from GeneTex

Prices $119.00
Sizes 25 μl
Host Rabbit
Clonality Polyclonal
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