Gene Symbol | COPG1 |
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Entrez Gene | 22820 |
Alt Symbol | COPG |
Species | Human |
Gene Type | protein-coding |
Description | coatomer protein complex, subunit gamma 1 |
Other Description | coat protein gamma-cop|coatomer subunit gamma|coatomer subunit gamma-1|gamma-1-COP|gamma-1-coat protein|gamma-COP|gamma-coat protein |
Swissprots | A8K6M8 B3KMF6 Q54AC4 Q9Y678 |
Accessions | EAW79267 EAW79268 EAW79269 EAW79270 Q9Y678 AB047846 BAB17657 AF100756 AAD43020 AK001724 BAG50968 AK024721 AK025147 AK123939 BAG53983 AK291693 BAF84382 AK309821 BC020498 AAH20498 BC066650 AAH66650 BU521557 XM_011512549 XP_011510851 NM_016128 NP_057212 |
Function | The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors. Required for limiting lipid storage in lipid droplets. Involved in lipid homeostasis by regulating the presence of perilipin family members PLIN2 and PLIN3 at the lipid droplet surface and promoting the association of adipocyte triglyceride lipase (PNPLA2) with the lipid droplet surface to mediate lipolysis (By |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:11056392}. Golgi apparatus membrane {ECO:0000269|PubMed:11056392}; Peripheral membrane protein {ECO:0000269|PubMed:11056392}; Cytoplasmic side {ECO:0000269|PubMed:11056392}. Cytoplasmic vesicle, COPI-coated vesicle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it. Predominantly located in the cis-Golgi apparatus. {ECO:0000250}. |
COPG / Gamma-COP Antibody Blocking Peptide - LS-E19990 from LifeSpan Bioscience
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COPG Blocking Peptide - 33R-6190 from Fitzgerald
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COPG fusion protein - Ag23434 from Proteintech Group
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COPG fusion protein - Ag3070 from Proteintech Group
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Recombinant Human COPG, GST-tagged - COPG-11457H from Creative Biomart
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Recombinant Human Coatomer subunit gamma-1(COPG1) ,partial - CSB-YP897307HU CSB-EP897307HU CSB-BP897307HU CSB-MP897307HU from Cusabio
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Recombinant Protein CopG(copG) - CSB-YP320297SMF CSB-EP320297SMF CSB-BP320297SMF CSB-MP320297SMF from Cusabio
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COPG Protein - abx164959 from Abbexa
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Gamma-coat protein - TP309018 from Acris Antibodies
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COPG Recombinant Protein Antigen - NBP1-85514PEP from Novus Biologicals
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COPG-Blocking-Peptide-C-term - BP19908b from Abgent, a WuXi AppTec company
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COPG1 Peptide, Human - M34GP03497H from Creative Peptides
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COPG Recombinant Protein Antigen - NBP2-55178PEP from Novus Biologicals
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COPG Recombinant Protein Antigen - NBP2-58317PEP from Novus Biologicals
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Coatomer subunit gamma-1 (COPG1), partial, Recombinant Protein - MBS1400877 from MyBioSource
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Protein CopG (copG), Recombinant Protein - MBS1246563 from MyBioSource
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