Gene Symbol | CCL2 |
---|---|
Entrez Gene | 6347 |
Alt Symbol | GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF |
Species | Human |
Gene Type | protein-coding |
Description | chemokine (C-C motif) ligand 2 |
Other Description | C-C motif chemokine 2|monocyte chemoattractant protein 1|monocyte chemoattractant protein-1|monocyte chemotactic and activating factor|monocyte chemotactic protein 1|monocyte secretory protein JE|small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je)|small inducible cytokine subfamily A (Cys-Cys), member 2|small-inducible cytokine A2 |
Swissprots | B2R4V3 Q9UDF3 P13500 |
Accessions | AAA18102 AAA36330 AAA60308 AAM54046 AAQ75526 BAA05080 CAC14049 EAW80211 EAW80212 P13500 AK311960 BAG34900 AV733621 BC009716 AAH09716 BG530064 BT007329 AAP35993 DQ893725 ABM84651 EU176175 ABW03626 M24545 AAA18164 M26683 AAA96708 M28226 AAA60309 S69738 AAB29926 X14768 CAA32876 NM_002982 NP_002973 |
Function | Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. |
Subcellular Location | Secreted. |
Top Pathways | Chagas disease (American trypanosomiasis), Malaria, Chemokine signaling pathway, Rheumatoid arthritis, NOD-like receptor signaling pathway |
MCP-1 Antibody - 2027 from Cell Signaling Technology
|
||||||||||
MCP-1-4/eotaxin (B-2) - sc-377082 from Santa Cruz Biotechnology
|
||||||||||
MCP-1 (5) - sc-130328 from Santa Cruz Biotechnology
|
||||||||||
MCP-1 (5D3-F7) - sc-32786 from Santa Cruz Biotechnology
|
||||||||||
MCP-1 (1A7B8) - sc-32819 from Santa Cruz Biotechnology
|
||||||||||
MCP-1 (5J) - sc-32771 from Santa Cruz Biotechnology
|
||||||||||
MCP-1 (C-17) - sc-1304 from Santa Cruz Biotechnology
|
||||||||||
MCP-1 (D9) - sc-32781 from Santa Cruz Biotechnology
|
||||||||||
MCP-1-4/eotaxin (FL-99) - sc-28971 from Santa Cruz Biotechnology
|
||||||||||
MCP-1 (S8) - sc-52877 from Santa Cruz Biotechnology
|
||||||||||
Anti-MCP1 antibody - ab9669 from Abcam
|
||||||||||
Anti-MCP1 antibody - ab7814 from Abcam
|
||||||||||
Anti-MCP1 antibody - ab73680 from Abcam
|
||||||||||
Anti-MCP1 antibody - ab9858 from Abcam
|
||||||||||
Anti-MCP1 antibody - ab106008 from Abcam
|
||||||||||
Anti-MCP1 antibody - ab18072 from Abcam
|
||||||||||
Anti-MCP1 antibody - ab166668 from Abcam
|
||||||||||
Anti-MCP1 antibody [2.2-4A4-1A11] - ab17715 from Abcam
|
||||||||||
Anti-MCP1 antibody [24822.11] - ab10390 from Abcam
|
||||||||||
Anti-MCP1 antibody [2H5] - ab21396 from Abcam
|
||||||||||
Anti-MCP1 antibody [2H5] (FITC) - ab93516 from Abcam
|
||||||||||
Anti-MCP1 antibody [2H5] (Phycoerythrin) - ab95558 from Abcam
|
||||||||||
Anti-MCP1 antibody [2H5] - Low endotoxin, Azide free - ab185743 from Abcam
|
||||||||||
Anti-MCP1 antibody [EP1361] - ab151538 from Abcam
|
||||||||||
Anti-MCP1 antibody [EP1361] (Alexa Fluor® 647) - ab200534 from Abcam
|