Gene Symbol | CCL2 |
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Entrez Gene | 6347 |
Alt Symbol | GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF |
Species | Human |
Gene Type | protein-coding |
Description | chemokine (C-C motif) ligand 2 |
Other Description | C-C motif chemokine 2|monocyte chemoattractant protein 1|monocyte chemoattractant protein-1|monocyte chemotactic and activating factor|monocyte chemotactic protein 1|monocyte secretory protein JE|small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je)|small inducible cytokine subfamily A (Cys-Cys), member 2|small-inducible cytokine A2 |
Swissprots | B2R4V3 Q9UDF3 P13500 |
Accessions | AAA18102 AAA36330 AAA60308 AAM54046 AAQ75526 BAA05080 CAC14049 EAW80211 EAW80212 P13500 AK311960 BAG34900 AV733621 BC009716 AAH09716 BG530064 BT007329 AAP35993 DQ893725 ABM84651 EU176175 ABW03626 M24545 AAA18164 M26683 AAA96708 M28226 AAA60309 S69738 AAB29926 X14768 CAA32876 NM_002982 NP_002973 |
Function | Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. |
Subcellular Location | Secreted. |
Top Pathways | Chagas disease (American trypanosomiasis), Malaria, Chemokine signaling pathway, Rheumatoid arthritis, NOD-like receptor signaling pathway |
Active human MCP1 full length protein - ab73866 from Abcam
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Active MCP1 full length protein - ab9670 from Abcam
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Active mouse MCP1 full length protein - ab9901 from Abcam
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Active pig MCP1 full length protein - ab88005 from Abcam
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Active rat MCP1 full length protein - ab73835 from Abcam
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Active rat MCP1 protein fragment - ab9780 from Abcam
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Cow MCP1 full length protein - ab177583 from Abcam
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Dog MCP1 full length protein - ab169727 from Abcam
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Guinea pig MCP1 full length protein - ab128552 from Abcam
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Human MCP1 full length protein - ab194178 from Abcam
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Human MCP1 full length protein - ab194186 from Abcam
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Human MCP1 full length protein - ab175164 from Abcam
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Human MCP1 full length protein - ab83822 from Abcam
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Human MCP1 full length protein - ab176087 from Abcam
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Human MCP1 peptide - ab73679 from Abcam
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MCP1 full length protein - ab87903 from Abcam
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Mouse MCP1 full length protein - ab156749 from Abcam
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Mouse MCP1 full length protein - ab184583 from Abcam
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Mouse MCP1 protein fragment - ab175172 from Abcam
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Mouse MCP1 protein fragment - ab176032 from Abcam
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Rabbit MCP1 full length protein - ab151202 from Abcam
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CCL2 / MCP1 Blocking Peptide - LS-E10741 from LifeSpan Bioscience
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CCL2 / MCP1 Antibody Blocking Peptide - LS-E8395 from LifeSpan Bioscience
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CCL2 / MCP1 Antibody Blocking Peptide - LS-E31392 from LifeSpan Bioscience
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ATF7IP / MCAF1 Antibody Blocking Peptide - LS-E13354 from LifeSpan Bioscience
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