CCL2
| Gene Symbol | CCL2 |
|---|---|
| Entrez Gene | 6347 |
| Alt Symbol | GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF |
| Species | Human |
| Gene Type | protein-coding |
| Description | chemokine (C-C motif) ligand 2 |
| Other Description | C-C motif chemokine 2|monocyte chemoattractant protein 1|monocyte chemoattractant protein-1|monocyte chemotactic and activating factor|monocyte chemotactic protein 1|monocyte secretory protein JE|small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je)|small inducible cytokine subfamily A (Cys-Cys), member 2|small-inducible cytokine A2 |
| Swissprots | B2R4V3 Q9UDF3 P13500 |
| Accessions | AAA18102 AAA36330 AAA60308 AAM54046 AAQ75526 BAA05080 CAC14049 EAW80211 EAW80212 P13500 AK311960 BAG34900 AV733621 BC009716 AAH09716 BG530064 BT007329 AAP35993 DQ893725 ABM84651 EU176175 ABW03626 M24545 AAA18164 M26683 AAA96708 M28226 AAA60309 S69738 AAB29926 X14768 CAA32876 NM_002982 NP_002973 |
| Function | Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. |
| Subcellular Location | Secreted. |
| Top Pathways | Chagas disease (American trypanosomiasis), Malaria, Chemokine signaling pathway, Rheumatoid arthritis, NOD-like receptor signaling pathway |
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