Gene Symbol | JDP2 |
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Entrez Gene | 122953 |
Alt Symbol | JUNDM2 |
Species | Human |
Gene Type | protein-coding |
Description | Jun dimerization protein 2 |
Other Description | jun dimerization protein 2|progesterone receptor co-activator |
Swissprots | O95430 Q9UIE4 J3KN58 Q8WYK2 |
Accessions | AAC98313 AAF21148 EAW81231 EAW81232 EAW81233 Q8WYK2 AB077880 BAB83896 AI916777 BC051303 AAH51303 BC068196 BE389064 BU740697 XM_005267332 XP_005267389 XM_006720032 XP_006720095 XM_011536431 XP_011534733 NM_001135047 NP_001128519 NM_001135048 NP_001128520 NM_001135049 NP_001128521 NM_130469 NP_569736 |
Function | Component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. Involved in a variety of transcriptional responses associated with AP-1 such as UV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. Can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN. May control transcription via direct regulation of the modification of histones and the assembly of chromatin. {ECO:0000269|PubMed:12707301, ECO:0000269|PubMed:12903123, ECO:0000269|PubMed:16026868, ECO:0000269|PubMed:16518400}. |
Subcellular Location | Nucleus {ECO:0000305}. |
Human JDP2 full length protein - ab132477 from Abcam
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Human JDP2 full length protein - ab156981 from Abcam
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Human JDP2 peptide - ab41625 from Abcam
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Human JDP2 protein fragment - ab153592 from Abcam
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JUNDM2 / JDP2 Antibody Blocking Peptide - LS-E11026 from LifeSpan Bioscience
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JUNDM2 / JDP2 Antibody Blocking Peptide - LS-E13411 from LifeSpan Bioscience
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JUNDM2 / JDP2 Antibody Blocking Peptide - LS-E13412 from LifeSpan Bioscience
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JDP2 Partial Recombinant Protein - H00122953-Q01 from Novus Biologicals
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JDP2 Recombinant Protein - H00122953-P01 from Novus Biologicals
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Recombinant Human JDP2 Protein - NBP2-23158 from Novus Biologicals
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Human JDP2 protein - orb191096 from Biorbyt
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JDP2 protein (His tag) - 80R-2773 from Fitzgerald
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JDP2 (1-163, His-tag) - AR50892PU-N from Acris Antibodies
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JDP2 (1-163, His-tag) - AR50892PU-S from Acris Antibodies
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JDP2 - H00122953-P01-10 from Acris Antibodies
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JDP2 - H00122953-P01-25 from Acris Antibodies
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JDP2 - H00122953-Q01-10 from Acris Antibodies
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JDP2 - H00122953-Q01-25 from Acris Antibodies
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JDP2, 1-163aa, Human His tag, E.coli - 01-P2068 from ARP American Research Products
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Recombinant Human Jun dimerization protein 2, His-tagged - JDP2-553H from Creative Biomart
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Recombinant Human Jun dimerization protein 2(JDP2) - CSB-YP011945HU CSB-EP011945HU CSB-BP011945HU CSB-MP011945HU from Cusabio
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JDP2, 1-163aa, Human His tag, E.coli - ATGP2068 from ATGen
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JDP2 Recombinant Protein Antigen - NBP2-31775PEP from Novus Biologicals
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JDP2 Peptide, Human - M34GP07859H from Creative Peptides
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JDP2 - PAT-82067-1 from Nordic BioSite
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