Gene Symbol | JDP2 |
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Entrez Gene | 122953 |
Alt Symbol | JUNDM2 |
Species | Human |
Gene Type | protein-coding |
Description | Jun dimerization protein 2 |
Other Description | jun dimerization protein 2|progesterone receptor co-activator |
Swissprots | O95430 Q9UIE4 J3KN58 Q8WYK2 |
Accessions | AAC98313 AAF21148 EAW81231 EAW81232 EAW81233 Q8WYK2 AB077880 BAB83896 AI916777 BC051303 AAH51303 BC068196 BE389064 BU740697 XM_005267332 XP_005267389 XM_006720032 XP_006720095 XM_011536431 XP_011534733 NM_001135047 NP_001128519 NM_001135048 NP_001128520 NM_001135049 NP_001128521 NM_130469 NP_569736 |
Function | Component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. Involved in a variety of transcriptional responses associated with AP-1 such as UV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. Can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN. May control transcription via direct regulation of the modification of histones and the assembly of chromatin. {ECO:0000269|PubMed:12707301, ECO:0000269|PubMed:12903123, ECO:0000269|PubMed:16026868, ECO:0000269|PubMed:16518400}. |
Subcellular Location | Nucleus {ECO:0000305}. |
Human JDP2 cDNA clone(NM_001135047.1) - CDFH009523 from Creative Biomart
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Human JDP2 cDNA clone(NM_001135049.1) - CDFH009524 from Creative Biomart
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Human JDP2 cDNA clone(NM_001135048.1) - CDFH009525 from Creative Biomart
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Human JDP2 ORF clone(NM_130469.3) - CDCH387507 from Creative Biomart
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Human JDP2 ORF Clone(NM_130469.3) - CDCL167566 from Creative Biomart
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Human JDP2 ORF Clone(NM_001135047.1) - CDCR350190 from Creative Biomart
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Human JDP2 ORF Clone(NM_001135047.1) - CDCR350191 from Creative Biomart
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Human JDP2 ORF Clone(NM_001135048.1) - CDCR350193 from Creative Biomart
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Human JDP2 ORF Clone(NM_001135048.1) - CDCR350194 from Creative Biomart
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Human JDP2 ORF Clone(NM_001135049.1) - CDCR350195 from Creative Biomart
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Human JDP2 ORF Clone(NM_001135049.1) - CDCR350196 from Creative Biomart
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Human JDP2 ORF clone(NM_130469.3) - CDCH387507 from Creative biogene
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Human JDP2 ORF Clone(NM_001135047.1) - CDCR350190 from Creative biogene
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Human JDP2 ORF Clone(NM_001135048.1) - CDCR350193 from Creative biogene
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Mouse JDP2 ORF clone (NM_001135049.1) - CDCL122375 from Creative biogene
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Human JDP2 cDNA Clone(NM_001135047.1) - CDFH009523 from Creative biogene
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Human JDP2 cDNA Clone(NM_001135049.1) - CDFH009524 from Creative biogene
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Human JDP2 cDNA Clone(NM_001135048.1) - CDFH009525 from Creative biogene
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