Gene Symbol | JDP2 |
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Entrez Gene | 122953 |
Alt Symbol | JUNDM2 |
Species | Human |
Gene Type | protein-coding |
Description | Jun dimerization protein 2 |
Other Description | jun dimerization protein 2|progesterone receptor co-activator |
Swissprots | O95430 Q9UIE4 J3KN58 Q8WYK2 |
Accessions | AAC98313 AAF21148 EAW81231 EAW81232 EAW81233 Q8WYK2 AB077880 BAB83896 AI916777 BC051303 AAH51303 BC068196 BE389064 BU740697 XM_005267332 XP_005267389 XM_006720032 XP_006720095 XM_011536431 XP_011534733 NM_001135047 NP_001128519 NM_001135048 NP_001128520 NM_001135049 NP_001128521 NM_130469 NP_569736 |
Function | Component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. Involved in a variety of transcriptional responses associated with AP-1 such as UV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. Can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN. May control transcription via direct regulation of the modification of histones and the assembly of chromatin. {ECO:0000269|PubMed:12707301, ECO:0000269|PubMed:12903123, ECO:0000269|PubMed:16026868, ECO:0000269|PubMed:16518400}. |
Subcellular Location | Nucleus {ECO:0000305}. |
JDP2 (C-16) - sc-23458 from Santa Cruz Biotechnology
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JDP2 (H-75) - sc-367695 from Santa Cruz Biotechnology
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JDP2 (N-16) - sc-23456 from Santa Cruz Biotechnology
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Anti-JDP2 antibody - ab40916 from Abcam
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Anti-JDP2 antibody - ab79506 from Abcam
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Anti-JUNDM2 / JDP2 Antibody (phospho-Thr148) - LS-C291203 from LifeSpan Bioscience
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Anti-JUNDM2 / JDP2 Antibody (N-Terminus) - LS-C146028 from LifeSpan Bioscience
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Anti-JUNDM2 / JDP2 Antibody (C-Terminus) - LS-C116095 from LifeSpan Bioscience
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Anti-JUNDM2 / JDP2 Antibody (N-Terminus) - LS-C116094 from LifeSpan Bioscience
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Anti-JUNDM2 / JDP2 Antibody (aa114-163) - LS-C199155 from LifeSpan Bioscience
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JDP2 Antibody - NBP2-31775 from Novus Biologicals
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JDP2 Antibody - H00122953-A01 from Novus Biologicals
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JDP2 Antibody (3C1) - H00122953-M01 from Novus Biologicals
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Monoclonal Anti-JDP2 antibody produced in mouse - SAB1411721 from Sigma-Aldrich
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Anti-JDP2 antibody produced in rabbit - SAB2106233 from Sigma-Aldrich
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Anti-JDP2 antibody produced in rabbit - HPA059511 from Sigma-Aldrich
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JDP2 antibody - N-terminal region (ARP31546_P050) - ARP31546_P050 from Aviva Systems Biology
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JDP2 antibody, N-term - GTX49080 from GeneTex
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JDP2 antibody, C-term - GTX49081 from GeneTex
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JDP2 Antibody (OAAF01639) - OAAF01639 from Aviva Systems Biology
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JDP-2 Antibody (Phospho-Thr148) (OAAF07842) - OAAF07842 from Aviva Systems Biology
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JDP2 antibody - H00122953-A01 from Acris Antibodies
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JDP2 antibody - H00122953-M01 from Acris Antibodies
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Mouse Anti-Human JDP2 - 101-10844 from RayBiotech
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Anti-Phospho-JDP2 (T148) antibody - STJ91259 from St John's Laboratory Ltd
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