CENPC

Gene Symbol	CENPC
Entrez Gene	1060
Alt Symbol	CENP-C, CENPC1, MIF2, hcp-4
Species	Human
Gene Type	protein-coding
Description	centromere protein C
Other Description	CENP-C 1\|centromere autoantigen C\|centromere autoantigen C1\|centromere protein C 1\|interphase centromere complex protein 7
Swissprots	Q8IW27 Q03188 Q9P0M5 Q6PIR0
Accessions	AAF73191 EAX05545 EAX05546 Q03188 AK307928 AK308170 AK308214 AK309437 BC030695 AAH30695 BC041117 AAH41117 BX648166 CD710556 M95724 AAA51974 XM_006714064 XP_006714127 XM_006714065 XP_006714128 XM_011531541 XP_011529843 XM_011531542 XP_011529844 XR_245245 XR_938676 NM_001812 NP_001803
Function	Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. CENPC recruits DNA methylation and DNMT3B to both centromeric and pericentromeric satellite repeats and regulates the histone code in these regions. {ECO:0000269\|PubMed:19482874, ECO:0000269\|PubMed:21529714}.
Subcellular Location	Nucleus {ECO:0000269\|PubMed:17651496}. Chromosome, centromere, kinetochore {ECO:0000269\|PubMed:17651496, ECO:0000269\|PubMed:19482874, ECO:0000269\|PubMed:21529714}. Note=Localizes exclusively in the kinetochore domain of centromeres. {ECO:0000269\|PubMed:21529714}.

CENP-C (C-6) - sc-166099 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Mouse
Clonality	Monoclonal

CENP-C (C-6): sc-166099. Western blot analysis of CENP-C expression in HeLa nuclear extract.

CENP-C (C-19) - sc-11286 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

CENP-C (H-300) - sc-22789 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Rabbit
Clonality	Polyclonal

CENP-C (H-300): sc-22789. Immuno?fluorescence staining of methanol-fixed HeLa cells showing nuclear local?ization.

CENP-C (L-19) - sc-11285 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

CENP-C (L-19): sc-11285. Immunofluorescence staining of methanol-fixed HeLa cells showing nucleolar and cytoplasmic localization.

Anti-CENPC antibody - ab33034 from Abcam

Prices	$387.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

All lanes : Anti-CENPC antibody (ab33034) at 1 µg/mlLane 1 : HeLa (Human epithelial carcinoma cell line) Whole Cell Lysate at 10 µgLane 2 : Jurkat (Human T cell lymphoblast-like cell line) Whole Cell Lysate (ab7899) at 20 µgSecondaryIR Dye 680 Conjugated Goat Anti-Rabbit IgG (H+L) at 1/15000 dilutionPerformed under reducing conditions.

Anti-CENPC antibody - ab107068 from Abcam

Prices	$376.00
Sizes	400 µl
Host	Rabbit
Clonality	Polyclonal

Anti-CENPC antibody (ab107068) at 1/100 dilution + Jurkat cell line lysates at 35 µg

Anti-CENPC antibody - ab124200 from Abcam

Prices	$376.00
Sizes	400 µl
Host	Rabbit
Clonality	Polyclonal

Anti-CENPC antibody (ab124200) at 1/100 dilution + Jurkat cell line lysates at 35 µg

Anti-CENPC antibody - ab171774 from Abcam

Prices	$376.00
Sizes	50 µl
Host	Mouse
Clonality	Polyclonal

All lanes : Anti-CENPC antibody (ab171774) at 1/500 dilutionLane 1 : CENPC-transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate secondary antibody at 1/2500 dilution

Anti-CENPC antibody [2159C5a] - ab50974 from Abcam

Prices	$382.00
Sizes	50 µg
Host	Mouse
Clonality	Monoclonal
Clone	2159C5a

ab36406 staining human lymphoblastoid cells by ICC/IF. Cells were PFA fixed and blocked with 1xPBS+1%BSA+0.5%Triton X-100 for 30 minutes at 25°C, prior to incubating with ab36406, diluted 1/250 for 24 hours at 4°C. An Alexa Fluor® 488 conjugated donkey anti-mouse antibody was used as the secondary.See Abreview

Anti-CENPC antibody [EPR15939] - ab193666 from Abcam

Prices	$384.00
Sizes	100 µl
Host	Rabbit
Clonality	Monoclonal
Clone	EPR15939

All lanes : Anti-CENPC antibody [EPR15939] (ab193666) at 1/5000 dilutionLane 1 : Jurkat cell lysateLane 2 : A431 cell lysateLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Anti-CENPC antibody - N-terminal - ab187354 from Abcam

Host	Rabbit
Clonality	Polyclonal

Anti-CENPC antibody - N-terminal (ab187354) at 1/1000 dilution + HeLa total cell extract

Anti-CENPC / CENP-C Antibody - LS-C79058 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Mouse
Clonality	Monoclonal

Anti-CENPC / CENP-C Antibody (clone 2159C5a) - LS-C184365 from LifeSpan Bioscience

Prices	$335.00
Sizes	50 µg
Host	Mouse
Clonality	Monoclonal
Clone	2159C5a

Anti-CENPC / CENP-C Antibody (aa448-475, AP) - LS-C254601 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-CENPC / CENP-C Antibody (aa448-475, APC) - LS-C254602 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-CENPC / CENP-C Antibody (aa448-475, Biotin) - LS-C254603 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-CENPC / CENP-C Antibody (aa448-475, Azide-free, HRP) - LS-C254606 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-CENPC / CENP-C Antibody (aa448-475, FITC) - LS-C254605 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-CENPC / CENP-C Antibody (aa448-475, PE) - LS-C254607 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-CENPC / CENP-C Antibody (aa394-424, AP) - LS-C254608 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-CENPC / CENP-C Antibody (aa394-424, APC) - LS-C254609 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-CENPC / CENP-C Antibody (aa394-424, FITC) - LS-C254611 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-CENPC / CENP-C Antibody (aa394-424, Biotin) - LS-C254610 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-CENPC / CENP-C Antibody (aa394-424, Azide-free, HRP) - LS-C254612 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-CENPC / CENP-C Antibody (aa394-424, PE) - LS-C254613 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

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