CENPC

Gene Symbol CENPC
Entrez Gene 1060
Alt Symbol CENP-C, CENPC1, MIF2, hcp-4
Species Human
Gene Type protein-coding
Description centromere protein C
Other Description CENP-C 1|centromere autoantigen C|centromere autoantigen C1|centromere protein C 1|interphase centromere complex protein 7
Swissprots Q8IW27 Q03188 Q9P0M5 Q6PIR0
Accessions AAF73191 EAX05545 EAX05546 Q03188 AK307928 AK308170 AK308214 AK309437 BC030695 AAH30695 BC041117 AAH41117 BX648166 CD710556 M95724 AAA51974 XM_006714064 XP_006714127 XM_006714065 XP_006714128 XM_011531541 XP_011529843 XM_011531542 XP_011529844 XR_245245 XR_938676 NM_001812 NP_001803
Function Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. CENPC recruits DNA methylation and DNMT3B to both centromeric and pericentromeric satellite repeats and regulates the histone code in these regions. {ECO:0000269|PubMed:19482874, ECO:0000269|PubMed:21529714}.
Subcellular Location Nucleus {ECO:0000269|PubMed:17651496}. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:17651496, ECO:0000269|PubMed:19482874, ECO:0000269|PubMed:21529714}. Note=Localizes exclusively in the kinetochore domain of centromeres. {ECO:0000269|PubMed:21529714}.

CENPC1-Over-expression-Lysate - LY12374a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag CENPC1 (arrow) using his tag antibody. 293T cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the LGALS10 gene

CENPC1 293T Cell Transient Overexpression Lysate(Denatured) - H00001060-T01 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

CENPC overexpression lysate - LY419733 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

CENPC1 293 Cell Lysate - 409238 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

CENPC Overexpression Lysate (Native) - NBL1-09083 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: CENPC Overexpression Lysate (Adult Normal) [NBL1-09083] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for CENPC.

CENPC1 Over-expression Lysate Product - GWB-DF011E from Genway Biotech

Category Cell Lysate
Prices $445.00
Sizes 100 µg
Species Human

CENPC Overexpression Lysate (Denatured) - H00001060-T01 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl

Panoply™ Human CENPC1 Knockdown Stable Cell Line - CSC-DC002965 from Creative biogene

Category Cell Line
Species Human
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