ANTXR1

Gene Symbol ANTXR1
Entrez Gene 84168
Alt Symbol ATR, GAPO, TEM8
Species Human
Gene Type protein-coding
Description anthrax toxin receptor 1
Other Description 2310008J16Rik|2810405N18Rik|tumor endothelial marker 8
Swissprots Q4ZFV6 J7K7G4 Q96P02 J7KF88 A8K7U8 Q9NVP3 Q9H6X2 Q53QD8
Accessions AAX88860 AAY24067 CAL60148 EAW99855 EAW99856 EAW99857 EAW99858 Q9H6X2 AF090095 AF279145 AAK52094 AF421380 AAL26496 AK001463 BAA91707 AK002160 AK025429 BAB15128 AK126783 AK223273 BAD96993 AK292113 BAF84802 AK309553 BC012074 AAH12074 BC012475 AAH12475 BU687536 CF126791 DC360415 DC361072 EU832615 ACE87706 EU832687 ACE87019 HQ447200 ADQ31687 JX424838 AFQ94038 JX424839 AFQ94039 XM_011533124 XP_011531426 XR_939725 XR_939726 NM_018153 NP_060623 NM_032208 NP_115584 NM_053034 NP_444262
Function Plays a role in cell attachment and migration. Interacts with extracellular matrix proteins and with the actin cytoskeleton. Mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. Plays a role in the angiogenic response of cultured umbilical vein endothelial cells. {ECO:0000269|PubMed:15777794, ECO:0000269|PubMed:16762926}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:16762926}; Single-pass type I membrane protein {ECO:0000269|PubMed:16762926}. Cell projection, lamellipodium membrane {ECO:0000269|PubMed:16762926}; Single-pass type I membrane protein {ECO:0000269|PubMed:16762926}. Cell projection, filopodium membrane {ECO:0000269|PubMed:16762926}; Single-pass type I membrane protein {ECO:0000269|PubMed:16762926}. Note=At the membrane of lamellipodia and at the tip of actin-enriched filopodia. Colocalizes with actin at the base of lamellipodia.
Tissue Specificity Detected in umbilical vein endothelial cells (at protein level). Highly expressed in tumor endothelial cells. {ECO:0000269|PubMed:15777794}.

TEM8 CRISPR/Cas9 KO Plasmid (h) - sc-404903 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TEM8 HDR Plasmid (h) - sc-404903-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TEM8 Double Nickase Plasmid (h) - sc-404903-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TEM8 Double Nickase Plasmid (h2) - sc-404903-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TEM8 CRISPR Activation Plasmid (h) - sc-404903-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TEM8 CRISPR Activation Plasmid (h2) - sc-404903-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TEM8 Lentiviral Activation Particles (h) - sc-404903-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TEM8 Lentiviral Activation Particles (h2) - sc-404903-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TEM8 siRNA (h) - sc-44144 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TEM8 shRNA Plasmid (h) - sc-44144-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TEM8 shRNA (h) Lentiviral Particles - sc-44144-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TEM8/ANTXR1 RNAi - H00084168-R05 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

TEM8/ANTXR1 RNAi - H00084168-R06 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

TEM8/ANTXR1 RNAi - H00084168-R04 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU092161 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN2508 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2508 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

ANTXR1 siRNA (Human) - CRJ3333 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ANTXR1 - MBS8206820 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ANTXR1 (NM_018153.3) - SHH237454 from Creative biogene

Category siRNA
Species Reactivities Human

Human ANTXR1 siRNA - orb273834 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ANTXR1 shRNA Plasmid (Human) - CHJ3333 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ANTXR1 miRNA 3'UTR clone - MiUTR3H-08427 from Creative biogene

Species Reactivities Human

ANTXR1 miRNA 3'UTR clone - MiUTR3H-08428 from Creative biogene

Species Reactivities Human

ANTXR1 miRNA 3'UTR clone - MiUTR4H-TG00376 from Creative biogene

Species Reactivities Human
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