ANTXR1

Gene Symbol	ANTXR1
Entrez Gene	84168
Alt Symbol	ATR, GAPO, TEM8
Species	Human
Gene Type	protein-coding
Description	anthrax toxin receptor 1
Other Description	2310008J16Rik|2810405N18Rik|tumor endothelial marker 8
Swissprots	Q4ZFV6 J7K7G4 Q96P02 J7KF88 A8K7U8 Q9NVP3 Q9H6X2 Q53QD8
Accessions	AAX88860 AAY24067 CAL60148 EAW99855 EAW99856 EAW99857 EAW99858 Q9H6X2 AF090095 AF279145 AAK52094 AF421380 AAL26496 AK001463 BAA91707 AK002160 AK025429 BAB15128 AK126783 AK223273 BAD96993 AK292113 BAF84802 AK309553 BC012074 AAH12074 BC012475 AAH12475 BU687536 CF126791 DC360415 DC361072 EU832615 ACE87706 EU832687 ACE87019 HQ447200 ADQ31687 JX424838 AFQ94038 JX424839 AFQ94039 XM_011533124 XP_011531426 XR_939725 XR_939726 NM_018153 NP_060623 NM_032208 NP_115584 NM_053034 NP_444262
Function	Plays a role in cell attachment and migration. Interacts with extracellular matrix proteins and with the actin cytoskeleton. Mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. Plays a role in the angiogenic response of cultured umbilical vein endothelial cells. {ECO:0000269|PubMed:15777794, ECO:0000269|PubMed:16762926}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:16762926}; Single-pass type I membrane protein {ECO:0000269|PubMed:16762926}. Cell projection, lamellipodium membrane {ECO:0000269|PubMed:16762926}; Single-pass type I membrane protein {ECO:0000269|PubMed:16762926}. Cell projection, filopodium membrane {ECO:0000269|PubMed:16762926}; Single-pass type I membrane protein {ECO:0000269|PubMed:16762926}. Note=At the membrane of lamellipodia and at the tip of actin-enriched filopodia. Colocalizes with actin at the base of lamellipodia.
Tissue Specificity	Detected in umbilical vein endothelial cells (at protein level). Highly expressed in tumor endothelial cells. {ECO:0000269|PubMed:15777794}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ANTXR1 Gene cDNA Clone - orb141817 from Biorbyt Prices $255.00 Sizes 10 μg Species Human

Human-ANTXR1-cDNA-Clone - DC03293 from Abgent, a WuXi AppTec company Prices $449.55 Sizes 10 µg Species Human Accession BC012074

ANTXR1 - MBS1271996 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC012074

Human ANTXR1 ORF Clone(NM_018153.3) - CDCL153942 from Creative Biomart Species Human Accession NM_018153.3

Human ANTXR1 ORF Clone(NM_032208.2) - CDCL153944 from Creative Biomart Species Human Accession NM_032208.2

Human ANTXR1 Gene cDNA clone plasmid - HG13367-G from Sino Biological Species Human

Human ANTXR1 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG13367-CM from Sino Biological Species Human

Human ANTXR1 Gene ORF cDNA clone expression plasmid, N-His tag - HG13367-NH from Sino Biological Species Human

Human ANTXR1 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG13367-ACR from Sino Biological Species Human

Human ANTXR1 Gene ORF cDNA clone expression plasmid, C-His tag - HG13367-CH from Sino Biological Species Human

Human ANTXR1 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG13367-ACG from Sino Biological Species Human

Human ANTXR1 Gene ORF cDNA clone expression plasmid, N-HA tag - HG13367-NY from Sino Biological Species Human

Human ANTXR1 Gene ORF cDNA clone expression plasmid - HG13367-UT from Sino Biological Species Human

Human ANTXR1 Gene ORF cDNA clone expression plasmid, C-HA tag - HG13367-CY from Sino Biological Species Human

Human ANTXR1 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG13367-NF from Sino Biological Species Human

Human ANTXR1 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG13367-NM from Sino Biological Species Human

Human ANTXR1 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG13367-CF from Sino Biological Species Human

Human ANTXR1 ORF Clone (BC012074) - CDCS414666 from Creative biogene Species Human Accession Q9H6X2

Human ANTXR1 ORF clone (BC012074) - CDCB159805 from Creative biogene Species Human

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