ANTXR1

Gene Symbol	ANTXR1
Entrez Gene	84168
Alt Symbol	ATR, GAPO, TEM8
Species	Human
Gene Type	protein-coding
Description	anthrax toxin receptor 1
Other Description	2310008J16Rik|2810405N18Rik|tumor endothelial marker 8
Swissprots	Q4ZFV6 J7K7G4 Q96P02 J7KF88 A8K7U8 Q9NVP3 Q9H6X2 Q53QD8
Accessions	AAX88860 AAY24067 CAL60148 EAW99855 EAW99856 EAW99857 EAW99858 Q9H6X2 AF090095 AF279145 AAK52094 AF421380 AAL26496 AK001463 BAA91707 AK002160 AK025429 BAB15128 AK126783 AK223273 BAD96993 AK292113 BAF84802 AK309553 BC012074 AAH12074 BC012475 AAH12475 BU687536 CF126791 DC360415 DC361072 EU832615 ACE87706 EU832687 ACE87019 HQ447200 ADQ31687 JX424838 AFQ94038 JX424839 AFQ94039 XM_011533124 XP_011531426 XR_939725 XR_939726 NM_018153 NP_060623 NM_032208 NP_115584 NM_053034 NP_444262
Function	Plays a role in cell attachment and migration. Interacts with extracellular matrix proteins and with the actin cytoskeleton. Mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. Plays a role in the angiogenic response of cultured umbilical vein endothelial cells. {ECO:0000269|PubMed:15777794, ECO:0000269|PubMed:16762926}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:16762926}; Single-pass type I membrane protein {ECO:0000269|PubMed:16762926}. Cell projection, lamellipodium membrane {ECO:0000269|PubMed:16762926}; Single-pass type I membrane protein {ECO:0000269|PubMed:16762926}. Cell projection, filopodium membrane {ECO:0000269|PubMed:16762926}; Single-pass type I membrane protein {ECO:0000269|PubMed:16762926}. Note=At the membrane of lamellipodia and at the tip of actin-enriched filopodia. Colocalizes with actin at the base of lamellipodia.
Tissue Specificity	Detected in umbilical vein endothelial cells (at protein level). Highly expressed in tumor endothelial cells. {ECO:0000269|PubMed:15777794}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human TEM8 full length protein - ab132123 from Abcam Category Protein Source Wheat germ Species Human

Human TEM8 peptide - ab39814 from Abcam Category Peptide Species Human

Human TEM8 peptide - ab41850 from Abcam Category Peptide Species Human

Human TEM8 peptide - ab41852 from Abcam Category Peptide Species Human

Human TEM8 peptide - ab23274 from Abcam Category Peptide Species Human

Human TEM8 protein fragment - ab125985 from Abcam Category Protein Source E. coli Species Human

ANTXR1 / TEM8 Antibody Blocking Peptide - LS-E25763 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ANTXR1 / TEM8 Antibody Blocking Peptide - LS-E18077 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ANTXR1 / TEM8 Antibody Blocking Peptide - LS-E7415 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ANTXR1 / TEM8 Antibody Blocking Peptide - LS-E7435 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ANTXR1 / TEM8 Antibody Blocking Peptide - LS-E9238 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ANTXR1 / TEM8 Antibody Blocking Peptide - LS-E30013 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

ANTXR1 / TEM8 Antibody Blocking Peptide - LS-E30014 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human TEM8/ANTXR1 Protein - H00084168-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human TEM8/ANTXR1 Protein - H00084168-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

TEM8/ANTXR1 Peptide - P1677 from Novus Biologicals Category Peptide Species Human

TEM8/ANTXR1 Peptide - P2796 from Novus Biologicals Category Peptide Species Human

Phospho-ANTXR1Y425-Antibody-Blocking-peptide - BP3603a from Abgent, a WuXi AppTec company Category Peptide Prices $120.00 Sizes 100 µg

Phospho-ANTXR1Y382-Antibody-Blocking-peptide - BP3547a from Abgent, a WuXi AppTec company Category Peptide Prices $120.00 Sizes 100 µg

ANTXR1-Antibody-Y382-Blocking-Peptide - BP7746a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human ANTXR1 protein - orb138188 from Biorbyt Category Protein Prices $357.00, $612.00 Sizes 20 μg, 50 μg Source Human Cells Species Human

ANTXR1 Immunizing peptide - orb17887 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg Species Human, Mouse, Rat

ANTXR1 Blocking Peptide - 33R-9794 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

TEM8 Blocking Peptide - 33R-10866 from Fitzgerald Category Peptide Prices $115.00 Sizes 50 µg

TEM8 Peptide - AC21-0592-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

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