ANTXR1

Gene Symbol	ANTXR1
Entrez Gene	84168
Alt Symbol	ATR, GAPO, TEM8
Species	Human
Gene Type	protein-coding
Description	anthrax toxin receptor 1
Other Description	2310008J16Rik|2810405N18Rik|tumor endothelial marker 8
Swissprots	Q4ZFV6 J7K7G4 Q96P02 J7KF88 A8K7U8 Q9NVP3 Q9H6X2 Q53QD8
Accessions	AAX88860 AAY24067 CAL60148 EAW99855 EAW99856 EAW99857 EAW99858 Q9H6X2 AF090095 AF279145 AAK52094 AF421380 AAL26496 AK001463 BAA91707 AK002160 AK025429 BAB15128 AK126783 AK223273 BAD96993 AK292113 BAF84802 AK309553 BC012074 AAH12074 BC012475 AAH12475 BU687536 CF126791 DC360415 DC361072 EU832615 ACE87706 EU832687 ACE87019 HQ447200 ADQ31687 JX424838 AFQ94038 JX424839 AFQ94039 XM_011533124 XP_011531426 XR_939725 XR_939726 NM_018153 NP_060623 NM_032208 NP_115584 NM_053034 NP_444262
Function	Plays a role in cell attachment and migration. Interacts with extracellular matrix proteins and with the actin cytoskeleton. Mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. Plays a role in the angiogenic response of cultured umbilical vein endothelial cells. {ECO:0000269|PubMed:15777794, ECO:0000269|PubMed:16762926}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:16762926}; Single-pass type I membrane protein {ECO:0000269|PubMed:16762926}. Cell projection, lamellipodium membrane {ECO:0000269|PubMed:16762926}; Single-pass type I membrane protein {ECO:0000269|PubMed:16762926}. Cell projection, filopodium membrane {ECO:0000269|PubMed:16762926}; Single-pass type I membrane protein {ECO:0000269|PubMed:16762926}. Note=At the membrane of lamellipodia and at the tip of actin-enriched filopodia. Colocalizes with actin at the base of lamellipodia.
Tissue Specificity	Detected in umbilical vein endothelial cells (at protein level). Highly expressed in tumor endothelial cells. {ECO:0000269|PubMed:15777794}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

ANTXR1-Over-expression-Lysate - LY11136a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

ANTXR1 overexpression lysate - LY409333 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

ANTXR1 293 Cell Lysate - 404937 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

ANTXR1 293 Cell Lysate - 406417 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

TEM8/ANTXR1 Overexpression Lysate (Native) - NBL1-07554 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

TEM8/ANTXR1 Overexpression Lysate (Native) - NBP2-06060 from Novus Biologicals Category Cell Lysate Prices $529.00 Sizes 100 µg

TEM8/ANTXR1 Overexpression Lysate (Native) - NBP2-05826 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

ANTXR1 Over-expression Lysate Product - GWB-6EA92B from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

ANTXR1 Over-expression Lysate Product - GWB-120659 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Human ANTXR1 HEK293 Cell Lysate (WB positive control) - 13367-H02HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human ANTXR1 Human Cells Transfected Lysate (positive control) (denatured) - orb174215 from Biorbyt Category Cell Lysate Prices $604.00 Sizes 300 μg Species Human

Panoply™ Human ANTXR1 Knockdown Stable Cell Line - CSC-DC000690 from Creative biogene Category Cell Line Species Human

Human ANTXR1 Knockout Cell Line-HeLa - CSC-RT1248 from Creative biogene Category Cell Line Species Human

ANTXR1 KO Cell Lysate-HeLa - CLKO-1101 from Creative biogene Category Cell Lysate

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