CTCF

Gene Symbol CTCF
Entrez Gene 10664
Alt Symbol MRD21
Species Human
Gene Type protein-coding
Description CCCTC-binding factor (zinc finger protein)
Other Description 11 zinc finger transcriptional repressor|11-zinc finger protein|CTCFL paralog|transcriptional repressor CTCF
Swissprots Q59EL8 Q53XI7 B5MC38 P49711
Accessions AAF31318 CAH05607 EAW83142 EAW83143 EAW83144 EAW83145 EAW83146 P49711 AA814313 AB209793 BAD93030 AI753629 AK093395 BAG52706 AK314804 BC014267 AAH14267 BT009915 AAP88917 DB229066 DQ895834 ABM86760 EU176369 ABW03820 U25435 AAB07788 XM_005255775 XP_005255832 NM_001191022 NP_001177951 NM_006565 NP_006556
Function Chromatin binding factor that binds to DNA sequence specific sites. Involved in transcriptional regulation by binding to chromatin insulators and preventing interaction between promoter and nearby enhancers and silencers. Acts as transcriptional repressor binding to promoters of vertebrate MYC gene and BAG1 gene. Also binds to the PLK and PIM1 promoters. Acts as a transcriptional activator of APP. Regulates APOA1/C3/A4/A5 gene cluster and controls MHC class II gene expression. Plays an essential role in oocyte and preimplantation embryo development by activating or repressing transcription. Seems to act as tumor suppressor. Plays a critical role in the epigenetic regulation. Participates in the allele-specific gene expression at the imprinted IGF2/H19 gene locus. On the maternal allele, binding within the H19 imprinting control region (ICR) mediates maternally inherited higher-order chromatin conformation to restrict enhancer access to IGF2. Plays a critical role in gene silencing over
Subcellular Location Nucleus, nucleoplasm. Chromosome. Chromosome, centromere. Note=May translocate to the nucleolus upon cell differentiation. Associates with both centromeres and chromosomal arms during metaphase. Associates with the H19 ICR in mitotic chromosomes. May be preferentially excluded from heterochromatin during interphase.
Tissue Specificity Ubiquitous. Absent in primary spermatocytes. {ECO:0000269|PubMed:9591631}.

CTCF - MBS1270296 from MyBioSource

Prices $175.00
Sizes 10ug plasmid + 200ul glycerol stock
Species Human
Accession BC014267

Human CTCF ORF Clone(NM_006565.3) - CDCL160000 from Creative Biomart

Species Human
Accession NM_006565.3

Human CTCF ORF Clone(NM_001191022.1) - CDCR357996 from Creative Biomart

Species Human
Accession NM_001191022.1

Human CTCF ORF Clone(NM_001191022.1) - CDCR357997 from Creative Biomart

Species Human
Accession NM_001191022.1

Human CTCF Gene cDNA Clone (full-length ORF Clone) - HG15017-G from Sino Biological

Species Human
Accession BC014267

Human CTCF natural ORF mammalian expression plasmid, N-GFPSpark tag - HG15017-ANG from Sino Biological

Species Human
Accession BC014267

Human CTCF natural ORF mammalian expression plasmid, N-Myc tag - HG15017-NM from Sino Biological

Species Human
Accession BC014267

Human CTCF natural ORF mammalian expression plasmid, C-OFPSpark tag - HG15017-ACR from Sino Biological

Species Human
Accession BC014267

Human CTCF natural ORF mammalian expression plasmid, N-OFPSpark tag - HG15017-ANR from Sino Biological

Species Human
Accession BC014267

Human CTCF natural ORF mammalian expression plasmid - HG15017-UT from Sino Biological

Species Human
Accession BC014267

Human CTCF ORF clone (NM_001191022.1) - CDCR051474 from Creative biogene

Species Human

Human CTCF ORF Clone (BC014267) - CDCS409238 from Creative biogene

Species Human
Accession P49711

Human CTCF ORF clone (BC014267) - CDCB158512 from Creative biogene

Species Human

Human CTCF Gene cDNA Clone - orb142687 from Biorbyt

Prices $264.00
Sizes 10 μg
Species Human
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