CIT

Gene Symbol CIT
Entrez Gene 11113
Alt Symbol CRIK, STK21
Species Human
Gene Type protein-coding
Description citron rho-interacting serine/threonine kinase
Other Description citron (rho-interacting, serine/threonine kinase 21)|citron Rho-interacting kinase|serine/threonine kinase 21|serine/threonine-protein kinase 21
Swissprots Q9UPZ7 O14578 Q6XUH8 Q86UQ9 Q2M5E1
Accessions AAB71327 EAW98155 EAW98156 EAW98157 EAW98158 O14578 AB023166 BAA76793 AK123136 AY209000 AAP43922 AY257469 AAP13528 AY681966 AAV87216 BC008127 BC047647 BC156529 AAI56530 BC172522 AAI72522 XM_006719206 XP_006719269 XM_011537783 XP_011536085 XM_011537784 XP_011536086 XM_011537785 XP_011536087 XM_011537786 XP_011536088 XM_011537787 XP_011536089 XM_011537788 XP_011536090 XM_011537789 XP_011536091 XM_011537790 XP_011536092 XM_011537791 XP_011536093 XM_011537792 XP_011536094 NM_001206999 NP_001193928 NM_007174 NP_009105
Function Plays a role in cytokinesis. Required for KIF14 localization to the central spindle and midbody. Putative RHO/RAC effector that binds to the GTP-bound forms of RHO and RAC1. It probably binds p21 with a tighter specificity in vivo. Displays serine/threonine protein kinase activity. Plays an important role in the regulation of cytokinesis and the development of the central nervous system. Phosphorylates MYL9/MLC2. {ECO:0000269|PubMed:16236794, ECO:0000269|PubMed:16431929, ECO:0000269|PubMed:21457715}.
Subcellular Location Cytoplasm {ECO:0000250}.

CRIK CRISPR/Cas9 KO Plasmid (h) - sc-417835 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CRIK HDR Plasmid (h) - sc-417835-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CRIK Double Nickase Plasmid (h) - sc-417835-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CRIK Double Nickase Plasmid (h2) - sc-417835-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CRIK CRISPR Activation Plasmid (h) - sc-417835-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CRIK CRISPR Activation Plasmid (h2) - sc-417835-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CRIK Lentiviral Activation Particles (h) - sc-417835-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CRIK Lentiviral Activation Particles (h2) - sc-417835-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CRIK siRNA (h) - sc-39214 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CRIK shRNA Plasmid (h) - sc-39214-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CRIK shRNA (h) Lentiviral Particles - sc-39214-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU006381 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

MISSION® siRNA - SIHK0426 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK0427 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK0425 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN2364 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2364 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CIT siRNA (Human) - CRH7601 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CIT - MBS8209903 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human Cit (NM_007174.2) - SHH264229 from Creative biogene

Category siRNA
Species Reactivities Human

Human CIT siRNA - orb268103 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CIT shRNA Plasmid (Human) - CHH7601 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CIT miRNA 3'UTR clone - MiUTR4H-TG02127 from Creative biogene

Species Reactivities Human
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